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EC number: 204-465-2
CAS number: 121-33-5
*solvent control with
In a reverse gene mutation assay in bacteria
(Lawlor, 1991), strains TA98, TA 100, TA 1535, TA 1537 and TA 1538 of S.
typhimurium were exposed to Vanillin (purity unknown), in DMSO at
concentrations of 100, 333, 667, 1000, 3330 and 5000 µg/plate in the
presence and absence of mammalian metabolic activation (plate
co-incubation method). Vanillin was tested up to the limit concentration
The positive controls induced the
appropriate responses in the corresponding strains. There was no
evidence of induced mutant colonies over background.
This study is classified as acceptable. This
study satisfies the requirement for Test Guideline EU B.13/14 for in
vitro mutagenicity (bacterial reverse gene mutation) data.
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