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EC number: 204-465-2
CAS number: 121-33-5
CIT report (2009) was chosen as key study, since conducted according to OECD guideline and GLP.Daphnids were exposed to test chemical at nominal concentrations of 0, 5.62, 10, 17.8, 31.6, 56.2 and 100 mg/L for 48 hours in static conditions. Immobilization was observed . The 48 hours EC50 was 36.79 mg/L, and the 48 hours NOEC was 26.8 mg/L.
Only one study on Vanilline was chosen as
key study, because it was conducted according to OECD guideline and GLP
on the results of this study, Vanilline is considered to be harmful to Daphnia
Another study on Natural Vanillin was chosen
as supporting study.
48-hours acute toxicity of Natural Vanillin (purity 98%) to Daphnia
magna was studied under static conditions. The
48-hours EC50 was higher than 10 mg/L but less than 100 mg/L (based on nominal
on the results of this study, Natural Vanilline is considered to be
harmful to Daphnia magna.
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