Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-465-2 | CAS number: 121-33-5
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- CAUJOLLE, MEYNIER and MOSCARELLA
- Year:
- 1 953
- Bibliographic source:
- C R Hebdo Seanc Acad Sci, Paris, 236, 2549 (citation)
- Reference Type:
- review article or handbook
- Title:
- No information
- Author:
- CLAYTON GD, CLAYTON FE
- Year:
- 1 993
- Bibliographic source:
- Patty's Industrial Hygiene and Toxicology , 4th Edit Vol II.A, 445-525
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- OPDYKE DLJ
- Year:
- 1 977
- Bibliographic source:
- Food Cosmet Toxicol, 15(6), 633-638
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- CAUJOLLE, MEYNIER and FARTHOUAT
- Year:
- 1 956
- Bibliographic source:
- C R Hebdo Seanc Acad Sci, Paris, 243, 609 (citation)
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- CAUJOLLE, MEYNIER and MOSCARELLA
- Year:
- 1 953
- Bibliographic source:
- C R Hebdo Seanc Acad Sci, Paris, 236, 2549 (citation)
- Reference Type:
- secondary source
- Title:
- No information
- Author:
- FRAZER
- Year:
- 1 967
- Bibliographic source:
- FAO/OMS Report Ser, vol 44A, 78 (citation)
Materials and methods
- Principles of method if other than guideline:
- See results
- GLP compliance:
- no
Test material
- Reference substance name:
- Vanillin
- EC Number:
- 204-465-2
- EC Name:
- Vanillin
- Cas Number:
- 121-33-5
- Molecular formula:
- C8H8O3
- IUPAC Name:
- 1-butoxypropan-2-ol
- Details on test material:
- no data
Constituent 1
Test animals
- Species:
- other: see results
Administration / exposure
- Route of administration:
- other: see results
Results and discussion
Effect levelsopen allclose all
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 160 mg/kg bw
- Remarks on result:
- other: rat by i.p. route
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 780 mg/kg bw
- Remarks on result:
- other: mouse by i.p. route
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 190 mg/kg bw
- Remarks on result:
- other: guinea pig by i.p. route
- Sex:
- not specified
- Dose descriptor:
- LDLo
- Effect level:
- 1 320 mg/kg bw
- Remarks on result:
- other: dog by i.v. route
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 500 mg/kg bw
- Remarks on result:
- other: rat by s.c. route
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
