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EC number: 204-465-2
CAS number: 121-33-5
RESULT OF THE TEST:
No. of animals with (+) reactions
In a dermal sensitization study (Hazleton, 1992) with Vanilline cristallisée (purity unknown) in ethanol, young adult Dunkin-Hartley guinea pigs (10/sex) were tested using the method of Maximization. Signs of irritation were noted during the induction. The macroscopic examinations did not reveal any lesion of delayed hypersensitivity in the 20 treated animals. No cutaneous abnormality was noted in the 20 guinea pigs examined in the control group. From the result obtained under the experimental conditions employed, vanillin did not provoke any reaction of cutaneous sensitization in the animals examined.
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