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EC number: 204-465-2
CAS number: 121-33-5
EC50 at 5 min = 0.38 mmol/l = 57.8 mg/l
Test performed with methanol as solvent (5 %)
Vanillin was investigated for its ready biodegradability in an OECD 301C test over 14 days . The percent biodegradation of the test item was calculated based on the biochemical oxygen demand (BOD) and reached 93% within the 14-day. Consequently, Vanillin was found to be readily biodegradable under the test conditions within 14 days and had no inhibitory effect on the activity of activated sludge microorganisms at the tested concentration of 100 mg/L, which can be used as a NOEC value.
from the key study mentioned above, most of the available data are on
growth inhibition test on Tetrahymena pyriformis has been
selected in supporting study and led to an IC50
(40H) = 163 mg/l
EC50 (210 min) = 179 mg/l has been reported on Saccharomyces
cerevisiae (Koch et al., 1993) and Microtox
tests gave EC50 (5 min) = 57.8 mg/l and EC50 (15 min) = 100.5 mg/l
(Cronin et al., 1981; Jin et al., 1999), however these data are not
recommended for STP microorganisms risk characterisation.
only data available on mixed inoculum concerned anaerobic sludge and
revealed an EC50 (49H) = 1800 mg/l on methane production inhibition
(Sierra-Alvarez & Lettinga, 1991).
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