1,2,4-trichlorobenzene

Toxicity to terrestrial plants

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

toxicity to terrestrial plants, other

Type of information:

other: EU Risk Assessment

Adequacy of study:

other information

Reliability:

other: EU Risk Assessment

Rationale for reliability incl. deficiencies:

other: No reliability is given as this is a summary entry for the EU RAR.

Principles of method if other than guideline:

EU Risk Assessment

GLP compliance:

not specified

EU Risk Assessment (2003):

 

Toxicity tests on higher plants are performed on lettuce, which was chosen because it is sensitive to different organic compounds and easy to handle. A part of the study has been performed in soilless solution, to test the sensitivity during continuous exposure of 1,2,4-TCB in water. For lettuce Lactuca sativa exposed in a semi-static test with the roots in water containing 1,2,4 -TCB, the EC50 (16-21 days) was 0.6 mg/l (Hulzebos et al., 1993).

 

The study on oats and turnip used a field soil with 1.54% OC. and performed in climate chambers (Ballhorn et al., 1984). Due to volatilisation in the open soil the EC50 (294 and 316 mg/kg dry soil) is not correct as a growth reduction was seen in the control plants probably affected by volatile substance or from condense water. The initial concentrations were used in the estimations. In Broecker et al. (1984), the same plants studied according to OECD TG 208 resulted in an EC50 of 40 mg/kg (EC0 of 10 mg/kg) for oats and an EC50 of 110 mg/kg (EC0 of 1) for turnips (Broecker et al., 1984).

Executive summary:

EU Risk Assessment, 2003:

 

Toxicity tests on higher plants are performed on lettuce, which was chosen because it is sensitive to different organic compounds and easy to handle. A part of the study has been performed in soilless solution, to test the sensitivity during continuous exposure of 1,2,4-TCB in water. For lettuce Lactuca sativa exposed in a semi-static test with the roots in water containing 1,2,4 -TCB, the EC50 (16-21 days) was 0.6 mg/l (Hulzebos et al., 1993).

The study on oats and turnip used a field soil with 1.54% OC. and performed in climate chambers (Ballhorn et al., 1984). Due to volatilisation in the open soil the EC₅₀ (294 and 316 mg/kg dry soil) is not correct as a growth reduction was seen in the control plants probably affected by volatile substance or from condense water. The initial concentrations were used in the estimations.

In Broecker et al. (1984), the same plants studied according to OECD TG 208 resulted in an EC₅₀ of 40 mg/kg (EC0 of 10 mg/kg) for oats and an EC50 of 110 mg/kg (EC0 of 1) for turnips (Broecker et al., 1984).

Reference 2

Endpoint:

toxicity to terrestrial plants, other

Type of information:

other: BUA report

Adequacy of study:

other information

Reliability:

other: BUA report

Rationale for reliability incl. deficiencies:

other: No reliability is given as this is a summary entry for the BUA report.

Principles of method if other than guideline:

BUA report

GLP compliance:

not specified

BUA report (1987):

 

On behalf of the Umweltbundesamt (UBA) the toxicity of 1,2,4 -TCB on Avena sativa and Brassica rapa was tested.

The two assigned laboratories found following results:

 

Avena sativa:

EC50 = 240 mg/kg (Broecker et al., 1984)

EC50 = 294 mg/kg (Ballhorn et al., 1984)

 

Brassica rapa:

EC50 = 110 mg/kg (Broecker et al., 1984)

EC50 = 316 mg/kg (Ballhorn et al., 1984)

Executive summary:

BUA report (1987):

 

On behalf of the Umweltbundesamt (UBA) the toxicity of 1,2,4 -TCB on Avena sativa and Brassica rapa was tested.

The two assigned laboratories found following results:

 

Avena sativa:

EC50 = 240 mg/kg (Broecker et al., 1984)

EC50 = 294 mg/kg (Ballhorn et al., 1984)

 

Brassica rapa:

EC50 = 110 mg/kg (Broecker et al., 1984)

EC50 = 316 mg/kg (Ballhorn et al., 1984)

Description of key information

For transported isolated intermediates according to REACh, Article 18, this endpoint is not a data requirement. However, data is available for this endpoint and is thus reported under the guidance of "all available data".

 

EU Risk Assessment, 2003:
Toxicity tests on higher plants are performed on lettuce, which was chosen because it is sensitive to different organic compounds and easy to handle. A part of the study has been performed in soilless solution, to test the sensitivity during continuous exposure of 1,2,4-TCB in water. For lettuce Lactuca sativa exposed in a semi-static test with the roots in water containing 1,2,4 -TCB, the EC50 (16-21 days) was 0.6 mg/l (Hulzebos et al., 1993).
The study on oats and turnip used a field soil with 1.54% OC. and performed in climate chambers (Ballhorn et al., 1984). Due to volatilisation in the open soil the EC50 (294 and 316 mg/kg dry soil) is not correct as a growth reduction was seen in the control plants probably affected by volatile substance or from condense water. The initial concentrations were used in the estimations.
In Broecker et al. (1984), the same plants studied according to OECD TG 208 resulted in an EC50 of 40 mg/kg (EC0 of 10 mg/kg) for oats and an EC50 of 110 mg/kg (EC0 of 1) for turnips (Broecker et al., 1984).

BUA report (1987):
On behalf of the Umweltbundesamt (UBA) the toxicity of 1,2,4 -TCB on Avena sativa and Brassica rapa was tested. The two assigned laboratories found following results:
Avena sativa:
EC50 = 240 mg/kg (Broecker et al., 1984)
EC50 = 294 mg/kg (Ballhorn et al., 1984)
Brassica rapa:
EC50 = 110 mg/kg (Broecker et al., 1984)
EC50 = 316 mg/kg (Ballhorn et al., 1984)