Registration Dossier
Registration Dossier
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EC number: 204-428-0 | CAS number: 120-82-1
Flash point
Administrative data
Link to relevant study record(s)
- Endpoint:
- flash point, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Flash point:
- 110 °C
- Remarks on result:
- other: The Atmospheric pressure is not reported.
- Executive summary:
Roempp, 2009
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C. The Atmospheric pressure is not reported.
- Endpoint:
- flash point, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- closed cup
- Specific details on test material used for the study:
- analytical purity: not specified
- Flash point:
- 110 °C
- Atm. press.:
- 1 013 hPa
- Executive summary:
CHEMSAFE, DECHEMA e.V., 2008
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C (closed cup).
- Endpoint:
- flash point, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Flash point:
- 110 °C
- Remarks on result:
- other: The Atmospheric pressure is not reported.
- Executive summary:
Ullmann, 2006
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C. The Atmospheric pressure is not reported.
- Endpoint:
- flash point, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- ASTM method D56-70, closed cup
- GLP compliance:
- not specified
- Type of method:
- closed cup
- Specific details on test material used for the study:
- analytical purity: not specified
- Flash point:
- 99 °C
- Atm. press.:
- 1 013 hPa
- Executive summary:
Kirk-Othmer, 2001
The flash point of 1,2,4-trichlorobenzene is reported as 99 °C (closed cup).
- Endpoint:
- flash point, other
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Flash point:
- 110 °C
- Remarks on result:
- other: The Atmospheric pressure is not reported.
- Executive summary:
Merck-Indey, 2001
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C. The Atmospheric pressure is not reported.
Referenceopen allclose all
recommended value
Flash point: 99°C
Description of key information
The individual study reports (data from handbooks or collection of data and (QSAR)calculations) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
Data of 1,2,4-trichlorobenzene on flash point range from 99 °C to 110 °C. Most indications of the flash point are at 110 °C.
CHEMSAFE, DECHEMA e.V., 2008
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C (closed cup).
Ullmann, 2006
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C. The Atmospheric pressure is not reported.
Merck-Indey, 2001
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C. The Atmospheric pressure is not reported.
Roempp, 2009
The flash point of 1,2,4-trichlorobenzene is reported as 110 °C. The Atmospheric pressure is not reported.
Kirk-Othmer, 2001
The flash point of 1,2,4-trichlorobenzene is reported as 99 °C (closed cup).
Key value for chemical safety assessment
- Flash point at 101 325 Pa:
- 110 °C
Additional information
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