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EC number: 204-428-0 | CAS number: 120-82-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water and sediment: simulation tests
Administrative data
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- 1980-1981
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable, well documented publication which meets basic scientific principles. (referring to Bartholomew and Pfaender, 1983)
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Influence of spatial and temporal variations on organic pollutant biodegradation rates in an estuarine environment.
- Author:
- Bartholomew GW and Pfaender FK
- Year:
- 1 983
- Bibliographic source:
- Applied and Environmental Microbiology, Vol. 45, No. 1, 103-109
- Reference Type:
- secondary source
- Title:
- 1,2,4-Trichlorbenzol - BUA-Stoffbericht 17 - (Dezember 1987) [Report in German]
- Author:
- Beratergremium für umweltrelevante Altstoffe (BUA)
- Year:
- 1 987
- Bibliographic source:
- Wissenschaftliche Verlagsgesellschaft VCH, Weinheim, ISSN: 0179-2601
Materials and methods
- Principles of method if other than guideline:
- Biodegradation rates were assessed by heterotrophic uptake kinetics (Pfaender and Bartholomew, 1982, Appl. Environ. Microbiol. 44:159-164). This protocol measures both the uptake of radiolabeled substrate into microbial cells and subsequent respiration to 14CO2. After incubation, the 14CO2 produced from respiration was trapped from the headspace above acidified samples, and substrate uptake into cells was determined by filtering the water sample through membrane filters.
- GLP compliance:
- no
Test material
- Reference substance name:
- 1,2,4-trichlorobenzene
- EC Number:
- 204-428-0
- EC Name:
- 1,2,4-trichlorobenzene
- Cas Number:
- 120-82-1
- Molecular formula:
- C6H3Cl3
- IUPAC Name:
- 1,2,4-trichlorobenzene
- Details on test material:
- - Name of test material (as cited in study report): 1,2,4-trichlorobenzene
- Analytical purity: no data
- Specific activity (if radiolabelling): 13.1 mCi/mmol
- Locations of the label (if radiolabelling): 1,2,4-trichloro[U-14C]benzene
Constituent 1
- Radiolabelling:
- yes
Study design
- Inoculum or test system:
- natural water
- Duration of test (contact time):
- >= 4 - <= 10 h
Results and discussion
Any other information on results incl. tables
summary of kinetic parameters for 1,2,4-trichlorobenzene
Date |
Site |
Temperature [°C] |
Vmaxa) [ng * l-1* h-1] |
Kmb) |
11-7-80 |
Upstream |
12 |
7.5 |
6.5 |
Estuarine |
14 |
<1 |
- |
|
Marine |
17 |
<1 |
- |
|
5-26-81 |
Upstream |
24 |
<1 |
- |
Estuarine |
28 |
7.9 |
7.0 |
|
Marine |
24 |
2.3 |
4.5 |
a) susbstrate uptake into cells. A Vmax< 1 ng * l-1* h-1represents a metabolic rate less than that detectable by this technique.
b) CO2production from respiration
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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