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Boiling point

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Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213 °C
Remarks on result:
other: Atmospheric pressure was not reported
Executive summary:

Roempp, 2009


The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213.5 °C
Atm. press.:
101.3 kPa
Executive summary:

Rossberg M (Ullmann's Encyclopedia of Industrial Chemistry), 2006


The boiling point of 1,2,4-trichlorobenzene was reported as 213.5 °C at 1013 hPa.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213.8 °C
Atm. press.:
101.3 kPa
Executive summary:

Kirk-Othmer, 2001


The boiling point of 1,2,4-Trichlorobenzene was reported as 213.8°C at 1013 hPa.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch scorDue to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213 °C
Remarks on result:
other: Atmospheric pressure was not reported.

Atmospheric pressure was not reported.

Executive summary:

Merck-Index, 2001


The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213.5 °C
Atm. press.:
1 013 hPa
Executive summary:

Rippen, 1991, Beilstein, 1978, Dreisbach, 1995, Hann,1977, Howard, 1989, IPCS, 1991


The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213.5 °C
Atm. press.:
1 013 hPa
Executive summary:

BUA/UBA, 1984


The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213 - 214 °C
Remarks on result:
other: Atmospheric pressure was not reported.
Executive summary:

Bolton, 1979


The boiling point of 1,2,4-Trichlorobenzene was reported between 213°C and 214 °C.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
212.9 °C
Atm. press.:
1 000 hPa
Executive summary:

Beilstein, 1978


The boiling point of 1,2,4-Trichlorobenzene was reported as 212.9 °C at 1000 hPa.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
211 °C
Atm. press.:
989 hPa
Executive summary:

Lock, 1933


The boiling point of 1,2,4-Trichlorobenzene was reported as 211°C at 989 hPa.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
213 °C
Remarks on result:
other: Atmospheric pressure was not reported.
Executive summary:

Beilstein, 1878, Bender, 1972, Hommel, 1994, Hooftman, 1982, Sax, 1984, Verschueren, 1983, Ware, 1977


The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
206 °C
Remarks on result:
other: Atmospheric pressure was not reported.
Executive summary:

Jungfleisch, 1868


The boiling point of 1,2,4-Trichlorobenzene was reported as 206 °C.

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Boiling pt.:
210 °C
Remarks on result:
other: Atmospheric pressure was not reported.
Executive summary:

Lesimple, 1866, Noelting 1905


The boiling point of 1,2,4-Trichlorobenzene was reported as 210°C.

Description of key information

The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.


 


The boiling point of 1,2,4-trichlorobenzene was determined in a series of experimental studies and is in the range of 213.5 °C - 213.8 °C at an atmospheric pressure of 1013 hPa. The melting point of 213.5 °C was chosen as key value for chemical safety assessment (reported by several individual references).


 


Roempp, 2009
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.



Rossberg M (Ullmann's Encyclopedia of Industrial Chemistry), 2006
The Boiling point of 1,2,4-trichlorobenzene was reported as 213.5 °C at 1013 hPa.



Kirk-Othmer, 2001
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.8°C at 1013 hPa.



Merck-Index, 2001
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.



Rippen, 1991, Beilstein, 1978, Dreisbach, 1995, Hann,1977, Howard, 1989, IPCS, 1991
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.



BUA/UBA, 1984
The boiling point of 1,2,4-Trichlorobenzene was reported as 213.5°C at 1013 hPa.



Bolton, 1979
The boiling point of 1,2,4-Trichlorobenzene was reported between 213°C and 214 °C.



Beilstein, 1978
The boiling point of 1,2,4-Trichlorobenzene was reported as 212.9 °C at 1000 hPa.



Lock, 1933
The boiling point of 1,2,4-Trichlorobenzene was reported as 211°C at 989 hPa



Beilstein, 1878, Bender, 1972, Hommel, 1994, Hooftman, 1982, Sax, 1984, Verschueren, 1983, Ware, 1977
The boiling point of 1,2,4-Trichlorobenzene was reported as 213°C.



Jungfleisch, 1868
The boiling point of 1,2,4-Trichlorobenzene was reported as 206 °C.



Lesimple, 1866, Noelting 1905
The boiling point of 1,2,4-Trichlorobenzene was reported as 210°C.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
213.5 °C

Additional information