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EC number: 204-428-0 | CAS number: 120-82-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 20 °C
- Vapour pressure:
- 0.26 hPa
- Executive summary:
ROEMPP Online, 2009
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection of data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 38.4 °C
- Vapour pressure:
- 0.13 kPa
- Temp.:
- 67.3 °C
- Vapour pressure:
- 0.67 kPa
- Temp.:
- 81.7 °C
- Vapour pressure:
- 1.33 kPa
- Temp.:
- 97.2 °C
- Vapour pressure:
- 2.67 kPa
- Temp.:
- 114.8 °C
- Vapour pressure:
- 5.33 kPa
- Temp.:
- 125.7 °C
- Vapour pressure:
- 8 kPa
- Temp.:
- 140 °C
- Vapour pressure:
- 13.3 kPa
- Temp.:
- 162 °C
- Vapour pressure:
- 26.7 kPa
- Temp.:
- 187.7 °C
- Vapour pressure:
- 53.3 kPa
- Temp.:
- 213.5 °C
- Vapour pressure:
- 101.3 kPa
- Executive summary:
Ullmann, 2006
Data of 1,2,4-trichlorobenzene on vapour pressure range from 130 Pa at 38.4 °C and 101,300 Pa at 213.5 °C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Only secondary literature
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 25 °C
- Vapour pressure:
- 0.46 mm Hg
- Executive summary:
Shiu, 1997
The vapour pressure of 1,2,4-trichlorobenzene was reported as 61 Pa at 25°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 25 °C
- Vapour pressure:
- 0.453 hPa
- Executive summary:
WHO, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 45.3 Pa at 25°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 25 °C
- Vapour pressure:
- 0.38 hPa
- Executive summary:
Rippen, 1991, EPA, 1985, UBA, 1984, Ware 1977
The vapour pressure of 1,2,4-trichlorobenzene was reported as 38 Pa at 25°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Only secondary literature
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 20 °C
- Vapour pressure:
- 0.31 hPa
- Executive summary:
Rippen, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 31 Pa at 20°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 38.4 °C
- Vapour pressure:
- 1.3 hPa
- Executive summary:
Howard, 1989, UBA 1984
The vapour pressure of 1,2,4-trichlorobenzene was reported as 130 Pa at 38.4 °C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 50 °C
- Vapour pressure:
- 2.02 hPa
- Executive summary:
Auer, 1988
The vapour pressure of 1,2,4-trichlorobenzene was reported as 202 Pa at 50°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed source, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 20 °C
- Vapour pressure:
- 0.26 hPa
- Executive summary:
Auer, 1988, Hommel, 1994
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 30 °C
- Vapour pressure:
- 0.54 hPa
- Executive summary:
Auer, 1988
The vapour pressure of 1,2,4-trichlorobenzene was reported as 54 Pa at 30°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 20 °C
- Vapour pressure:
- 26.3 Pa
- Executive summary:
Korte, 1986
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26.3 Pa at 20°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Original report not available
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 25 °C
- Vapour pressure:
- 0.56 hPa
- Executive summary:
Hooftman, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 56 Pa at 25°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 20 °C
- Vapour pressure:
- 0.32 hPa
- Executive summary:
GSF, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 32 Pa at 20°C.
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
- Principles of method if other than guideline:
- secondary peer reviewed scoure, valid collection af data
- GLP compliance:
- not specified
- Type of method:
- other: no data
- Specific details on test material used for the study:
- analytical purity: not specified
- Temp.:
- 20 °C
- Vapour pressure:
- 0.4 hPa
- Executive summary:
Beilstein, 1978
The vapour pressure of 1,2,4-trichlorobenzene was reported as 40 Pa at 20°C.
Referenceopen allclose all
Conversion from mm Hg to Pa: 1 mm Hg = 133 Pa
Description of key information
The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.
The vapor pressure of 1,2,4-trichlorobenzene was determined in a series of experimental studies and is 26 Pa to 61 Pa in the temperature range from 20 °C to 25 °C. The mean value of 43.5 Pa at room temperature was chosen as key value for chemical safety assessment.
Experiments at temperatures between 38.4 °C and 213.5 °C show vapor pressures between 130 Pa and 101300 Pa.
ROEMPP Online, 2009
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.
Ullmann, 2006
Data of 1,2,4-trichlorobenzene on vapour pressure range from 130 Pa at 38.4 °C and 101,300 Pa at 213.5 °C.
Shiu, 1997
The vapour pressure of 1,2,4-trichlorobenzene was reported as 61 Pa at 25°C.
WHO, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 45.3 Pa at 25°C.
Rippen, 1991, EPA, 1985, UBA, 1984, Ware 1977
The vapour pressure of 1,2,4-trichlorobenzene was reported as 38 Pa at 25°C.
Rippen, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 31 Pa at 20°C.
Howard, 1989, UBA 1984
The vapour pressure of 1,2,4-trichlorobenzene was reported as 130 Pa at 38.4 °C.
Auer, 1988
The vapour pressure of 1,2,4-trichlorobenzene was reported as 202 Pa at 50°C.
Auer, 1988, Hommel, 1994
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.
Korte, 1986
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26.3 Pa at 20°C.
Hooftman, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 56 Pa at 25°C.
GSF, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 32 Pa at 20°C.
Key value for chemical safety assessment
- Vapour pressure:
- 43.5 Pa
- at the temperature of:
- 20 °C
Additional information
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