Registration Dossier

Diss Factsheets

Physical & Chemical properties

Vapour pressure

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
20 °C
Vapour pressure:
0.26 hPa
Executive summary:

ROEMPP Online, 2009


The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection of data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
38.4 °C
Vapour pressure:
0.13 kPa
Temp.:
67.3 °C
Vapour pressure:
0.67 kPa
Temp.:
81.7 °C
Vapour pressure:
1.33 kPa
Temp.:
97.2 °C
Vapour pressure:
2.67 kPa
Temp.:
114.8 °C
Vapour pressure:
5.33 kPa
Temp.:
125.7 °C
Vapour pressure:
8 kPa
Temp.:
140 °C
Vapour pressure:
13.3 kPa
Temp.:
162 °C
Vapour pressure:
26.7 kPa
Temp.:
187.7 °C
Vapour pressure:
53.3 kPa
Temp.:
213.5 °C
Vapour pressure:
101.3 kPa
Executive summary:

Ullmann, 2006


Data of 1,2,4-trichlorobenzene on vapour pressure range from 130 Pa at 38.4 °C and 101,300 Pa at 213.5 °C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Only secondary literature
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
25 °C
Vapour pressure:
0.46 mm Hg

Conversion from mm Hg to Pa: 1 mm Hg = 133 Pa

Executive summary:

Shiu, 1997


The vapour pressure of 1,2,4-trichlorobenzene was reported as 61 Pa at 25°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
25 °C
Vapour pressure:
0.453 hPa
Executive summary:

WHO, 1991


The vapour pressure of 1,2,4-trichlorobenzene was reported as 45.3 Pa at 25°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
25 °C
Vapour pressure:
0.38 hPa
Executive summary:

Rippen, 1991, EPA, 1985, UBA, 1984, Ware 1977


The vapour pressure of 1,2,4-trichlorobenzene was reported as 38 Pa at 25°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Only secondary literature
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
20 °C
Vapour pressure:
0.31 hPa
Executive summary:

Rippen, 1991


The vapour pressure of 1,2,4-trichlorobenzene was reported as 31 Pa at 20°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
38.4 °C
Vapour pressure:
1.3 hPa
Executive summary:

Howard, 1989, UBA 1984


The vapour pressure of 1,2,4-trichlorobenzene was reported as 130 Pa at 38.4 °C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
50 °C
Vapour pressure:
2.02 hPa
Executive summary:

Auer, 1988


The vapour pressure of 1,2,4-trichlorobenzene was reported as 202 Pa at 50°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed source, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
20 °C
Vapour pressure:
0.26 hPa
Executive summary:

Auer, 1988, Hommel, 1994


The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
30 °C
Vapour pressure:
0.54 hPa
Executive summary:

Auer, 1988


The vapour pressure of 1,2,4-trichlorobenzene was reported as 54 Pa at 30°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
20 °C
Vapour pressure:
26.3 Pa
Executive summary:

Korte, 1986


The vapour pressure of 1,2,4-trichlorobenzene was reported as 26.3 Pa at 20°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original report not available
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
25 °C
Vapour pressure:
0.56 hPa
Executive summary:

Hooftman, 1982


The vapour pressure of 1,2,4-trichlorobenzene was reported as 56 Pa at 25°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
20 °C
Vapour pressure:
0.32 hPa
Executive summary:

GSF, 1982


The vapour pressure of 1,2,4-trichlorobenzene was reported as 32 Pa at 20°C.

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Justification for type of information:
Due to insufficient reporting of the experimental details, this study was rated with a Klimisch score of 4 (‘not assignable’). As none of the available studies can serve as a key study with a sufficiently detailed reporting justifying a Klimisch score of 1 or 2 for the given endpoint, several independent sources were used in a weight of evidence approach. The combined data from handbooks or collection of data provide experimental values in a similar range, supporting the reliability of the result.
Principles of method if other than guideline:
secondary peer reviewed scoure, valid collection af data
GLP compliance:
not specified
Type of method:
other: no data
Specific details on test material used for the study:
analytical purity: not specified
Temp.:
20 °C
Vapour pressure:
0.4 hPa
Executive summary:

Beilstein, 1978


The vapour pressure of 1,2,4-trichlorobenzene was reported as 40 Pa at 20°C.

Description of key information

The individual study reports (data from handbooks or collection of data) show some deficiencies with respect to the comprehensiveness of the experimental details. Therefore, a reliability of 1 or 2 and thus adequacy as key study was not assignable for any of the individual studies. Consequently, the studies were assigned a Klimisch score of 4 (according to guidance document R.4, ‘not assignable: studies or data […] which are only listed in short abstracts or secondary literature (books, reviews, etc.)). As the individual studies report values are in a similar range, collectively, these studies can be used to conclude on this endpoint and to satisfy the information requirement.


 


The vapor pressure of 1,2,4-trichlorobenzene was determined in a series of experimental studies and is 26 Pa to 61 Pa in the temperature range from 20 °C to 25 °C. The mean value of 43.5 Pa at room temperature was chosen as key value for chemical safety assessment.
Experiments at temperatures between 38.4 °C and 213.5 °C show vapor pressures between 130 Pa and 101300 Pa.


 


ROEMPP Online, 2009
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.



Ullmann, 2006
Data of 1,2,4-trichlorobenzene on vapour pressure range from 130 Pa at 38.4 °C and 101,300 Pa at 213.5 °C.



Shiu, 1997
The vapour pressure of 1,2,4-trichlorobenzene was reported as 61 Pa at 25°C.



WHO, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 45.3 Pa at 25°C.



Rippen, 1991, EPA, 1985, UBA, 1984, Ware 1977
The vapour pressure of 1,2,4-trichlorobenzene was reported as 38 Pa at 25°C.



Rippen, 1991
The vapour pressure of 1,2,4-trichlorobenzene was reported as 31 Pa at 20°C.



Howard, 1989, UBA 1984
The vapour pressure of 1,2,4-trichlorobenzene was reported as 130 Pa at 38.4 °C.



Auer, 1988
The vapour pressure of 1,2,4-trichlorobenzene was reported as 202 Pa at 50°C.



Auer, 1988, Hommel, 1994
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26 Pa at 20°C.


 


Korte, 1986
The vapour pressure of 1,2,4-trichlorobenzene was reported as 26.3 Pa at 20°C.



Hooftman, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 56 Pa at 25°C.



GSF, 1982
The vapour pressure of 1,2,4-trichlorobenzene was reported as 32 Pa at 20°C.

Key value for chemical safety assessment

Vapour pressure:
43.5 Pa
at the temperature of:
20 °C

Additional information