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EC number: 204-428-0 | CAS number: 120-82-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Henry's Law constant
Administrative data
- Endpoint:
- Henry's law constant
- Type of information:
- other: EU Risk Assessment
- Adequacy of study:
- other information
- Reliability:
- other: EU Risk Assessment
- Rationale for reliability incl. deficiencies:
- other: No reliability is given as this is a summary entry for the EU RAR.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 2 003
- Reference Type:
- publication
- Title:
- Temperature dependence of Henrys Law constants for selected chlorobenzenes, polychlorinated biphenyls and polycyclic aromatic hydrocarbons.
- Author:
- ten Hulscher TEM, van der Velde LE, Bruggeman WA
- Year:
- 1 992
- Bibliographic source:
- Environ. Toxicol. Chem., 11, 1595-1603.
- Reference Type:
- publication
- Title:
- Desorption of chlorinated hydrocarbons from spiked and anthropogenically contaminated sediments.
- Author:
- Oliver BG
- Year:
- 1 985
- Bibliographic source:
- Chemosphere, 14(8), 1087-1106.
- Reference Type:
- publication
- Title:
- Air-water partitioning coefficients of organics in dilute aqueous solutions.
- Author:
- Ashworth RA, Howe GB, Mullins ME, Rogers TN
- Year:
- 1 988
- Bibliographic source:
- J. Haz. Mater. 18, 25-36.
- Reference Type:
- publication
- Title:
- Estimation programs interface for Microsoft Windows 3.1. By Meylan W, Howard P.
- Author:
- EPIWIN
- Year:
- 1 995
- Bibliographic source:
- Syracuse Research Corporation, Syracuse, NY
- Reference Type:
- publication
- Title:
- The effects of organic environmental chemicals on the growth of the alga Scenedesmus subspicatus: A contribution to environmental biology.
- Author:
- Geyer H, Scheunert I, Korte F
- Year:
- 1 985
- Bibliographic source:
- Chemosphere, 14 (9), 1355-1369.
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 986
- Reference Type:
- publication
- Title:
- Biodegradation of 1,2,3- and 1,2,4-trichlorobenzene in soil and in liquid enrichment culture.
- Author:
- Marinucci AC and Bartha R
- Year:
- 1 979
- Bibliographic source:
- Appl. Environ. Microbiol., 38(5), 811-817.
Materials and methods
- Principles of method if other than guideline:
- EU Risk Assessment
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,2,4-trichlorobenzene
- EC Number:
- 204-428-0
- EC Name:
- 1,2,4-trichlorobenzene
- Cas Number:
- 120-82-1
- Molecular formula:
- C6H3Cl3
- IUPAC Name:
- 1,2,4-trichlorobenzene
Constituent 1
Results and discussion
Any other information on results incl. tables
EU Risk Assessment (2003):
Conclusion on volatility
The volatilisation of 1,2,4-TCB in clean water may be high but will be reduced in natural surface water according to the depth of the water body, possible stratification or turbulence of the water body and to the content of dissolved organic carbon (DOC) and particulate organic carbon (POC). The volatilisation is slow from soil and sludge because adsorption to organic carbon takes place.
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Volatility
Volatilisation from surface water is estimated by means of 1,2,4-TCBs Henrys Law constant (H). Using a vapour pressure of 36 Pa at 20°C and a water solubility of 36 mg/l, the estimated Henry's Law constant would be 181 Pa*m3/mol which indicates that volatilisation from shallow waters and after accidental spillage to water may take place.
A more reliable value may be obtained by measuring H directly by direct measurement of concentrations in the gas phase and the water phase in a system at equilibrium. Using a gas-purge technique, a water concentration of 10µg/l and GC determination, ten Hulscher et al. (1992) measured the dimensionless Henrys Law constant (Kair-water) to 0.041 equivalent to a H of 101 Pa.m3/mol for 1,2,4-TCB. The measurements were carried out in a buffer solution at pH 6.4 which may have changed the solubility of 1,2,4 -TCB. Other measured values ofH at 20ºC were 122 Pa.m3/mol(Kair-water 0.050) and 185 Pa.m3/mol (Kair-water 0.076) (Oliver, 1985; Ashworth et al., 1988, respectively).
QSAR estimation of Henry's Law constant by the bond contribution method resulted in a H estimated to be 2.19*10-3 atm.m3/mol (290 Pa.m3/mol) (EPIWIN, 1995).
The volatilisation rate in an aqueous solution has been observed to be 6.5 hour/m depth at 20°C (Geyer et al., 1985). The volatility from an aqueous solution was studied using the water sampling method. The initial concentration was 10.7 mg/l and the half-life was estimated to be 22 minutes at 20°C using 14C-labelled substance (Korte and Freitag, 1986). These studies confirm that volatilisation takes place but the results are not in a form that can be used quantitatively in this risk assessment.
The volatilisation from soil is reduced at increasing content of organic matter due to adsorption. In soil incubated with 1,2,4-TCB at the concentration 50 ppm, the amount of volatile substances recovered from the test systems was 4 to 18% of the initial concentration from soil with high organic matter and 20 to 40% at low organic matter (Marinucci and Bartha, 1979).
Applicant's summary and conclusion
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