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EC number: 202-500-6
CAS number: 96-33-3
After administration in a closed cup on skin (46 mg/kg bw), a slow
penetration in dermis occurred and low levels were found in the kidneys
and bladder within 4 hours. After penetration of the dermis, which
occurred between 6 and 40 hours, a gradual increase of radioactivity
occurred in the heart, liver, lungs, tear glands, and other subcutaneous
tissues throughout the body. The detoxification was screened by
estimating the urinary thioether content and respiratory carbon
monoxide. This showed that in addition to oxidation to CO2, the binding
to SH-groups was the principal means of metabolism.
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