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EC number: 203-628-5
CAS number: 108-90-7
Year: 1971 (unclear if "Year of test guideline" or "Year of study completion".)
Mortality: 4 out of 8 of the high dose after 14 - 21 daily
doses; clinical studies prior to death revealed an increase
in immature leucocytes, low blood sugar, elevated serum
glutamic-pyruvic transaminase and alkaline phosphatase, and
in some dogs, increases in total bilirubin and total
cholesterol. At the high level, there were gross and/or
microscopic pathology in liver, kidney, gastrointestinal
mucosa, and hematopoietic tissue of the dogs which died and,
less extensively, in the dogs which were sacrificed at the
end of the exposure period. No consistent signs of chloro-
benzene effects were evident in the dogs at the intermediate
and low levels.
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