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EC number: 203-149-1
CAS number: 103-83-3
6 healthy volunteers in an exposure chamber were exposed against 20, 45,
or 80 µm/m³ for 8 hours DMBA uptake by inhalation was 76%.DMBA
was quickly distributed and biotransformed to nearly 100 %. DMBA was
eliminated by expired air ranging from 3 % to 6 %. The excretion of
DMBA in urine increased rapidly during exposure period and decreased
quickly after the end of exposure. More than 50 % was eleminated within
2 hours of exposure. DMBA was eleminated in the urine with a half time
of 4.3 h (range. 4.2-4.8 h). The total amound of DMBA excreted during
the exposure and post exposure for up to 24 hours, expressed as a
fraction of the total respiratory uptake, was 90 % (range: 63-146 %).
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