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EC number: 204-427-5
CAS number: 120-80-9
Primary Irritation scores, Intact and
abraded skin on rabbits (0.5 g, 24h period):
Primary Irritation score: 5.5
a primary dermal irritation study (Flickinger, 1976), 6
albino rabbits were
dermally exposed to 0.5 mg of
to bellies. No indication was done concerning dressing.
Skin of animals was abraded or intact. Animals
then were observed for 14 days. Irritation was scored by the method of Draize.
The contact of catechol produced slight to moderate erythema (score 2.2) and slight oedema (score 1.2) after 24 hours
on intact skin.
irritation was less marked 72 h after exposure
(erythema: 1.7 and oedema: 1.0).
this study, Catechol is irritating
to the skin based on Draize scoring.
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