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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
significant methodological deficiencies
Remarks:
The endpoint of the study is not relevant.

Data source

Reference
Reference Type:
publication
Title:
No information
Author:
Ortega A., Domingo J.L., Gomez M., Corbella J.
Year:
1989
Bibliographic source:
Pharmacology and Toxicology, 64, 247-251.

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
not specified
Limit test:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Pyrocatechol
EC Number:
204-427-5
EC Name:
Pyrocatechol
Cas Number:
120-80-9
Molecular formula:
C6H6O2
IUPAC Name:
pyrocatechol
Details on test material:
no data

Test animals

Species:
mouse
Strain:
Swiss
Sex:
male

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
other: One-fourth of the LD50
Effect level:
68 mg/kg bw

Applicant's summary and conclusion