Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 204-427-5 | CAS number: 120-80-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
Among the studies available in the literature on terrestrial ecotoxicity, only one of them, performed on earthworms, was reliable (Hartenstein, 1982). Despite it did not follow any guideline, it was scored as a reliability 2 and flagged as a key study. Indeed, it was fully described, the test species is that recommended in the current guidances and the measured parameters are relevant indicators of toxicity. Eisenia foetida hatchlings were exposed for 42 days to catechol concentrations of 50, 500, 2000 and 4000 mg/kg dw. Based on mortality, catechol presented 42d-NOEC and -LOEC of 2000 and 4000 mg/kg dw. Based on growth, catechol presented 42d-NOEC and -LOEC of 500 and 2000 mg/kg dw.
For the other terrestrial organisms (i.e. plants, arthropods, soil micro-organisms, birds), there is either no data at all, or no reliable data.
As recommended in the ECHA guidance on information requirements and chemical safety assessment - Chapter R10, when there is only one terrestrial result, the risk assessment, and thus the PNEC derivation, should be performed both on this test result and on the basis of the outcome of the aquatic toxicity data using the equilibrium partitioning method. As a matter of precaution, the more conservative PNEC must be retained. Based on the PNECs calculated in the "Ecotoxicological information" section of the IUCLID, the PNEC derivated from the equilibrium partitioning theory method is retained for chemical safety assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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