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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Remarks:
Data comes from a peer-reviewed handbook cited among "reference books containing peer-reviewed physico-chemical data" in the ECHA guidance document on information requirements and chemical safety assessment (R.7a).
Reason / purpose for cross-reference:
reference to same study
Qualifier:
no guideline available
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Medium:
other: ethyl alcohol
Solubility:
740 g/L
Temp.:
60 °C
Medium:
other: ethyl ether
Solubility:
653 g/L
Temp.:
60 °C
Medium:
acetone
Solubility:
752 g/L
Temp.:
60 °C
Medium:
benzene
Solubility:
73 g/L
Temp.:
60 °C
Medium:
other: chloroform
Solubility:
7 g/L
Temp.:
60 °C
Medium:
other: carbon tetrachloride
Solubility:
8 g/L
Temp.:
60 °C
Conclusions:
Catechol is soluble to very soluble in the organic solvents cited in this handbook.
Executive summary:

This peer-reviewed handbook reported solubility values at 60°C in different organic solvents (ethyl alcohol, ethyl ether, acetone, benzene, chloroform, carbon tetrachloride). Depending on the solvents, the values ranged from 7 to 752 g/L; indicating that catechol is soluble to very soluble in these organic solvents.

Description of key information

Solubility at 20°C: 660 g/L in acetone; 582 g/L in ethanol; 19 g/L in chloroform; 1 g/L in carbon tetrachloride; 8 g/L in benzene.
Solubility at 25°C: 740 g/L in ethyl alcohol; 653 g/L in ethyl ether; 752 g/L in acetone; 73 g/L in benzene; 7 g/L in chloroform.
Catechol is soluble to very soluble in these organic solvents.

Key value for chemical safety assessment

Additional information

A reference peer-reviewed handbook and publications give consistent values of solubility in organic solvents.  One key study (klimish 2) and two supporting studies (klimish 4) are available.