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EC number: 204-427-5
CAS number: 120-80-9
Hartenstein (1982) investigated the chronic
effects of catechol on Eisenia foetida. No particular guideline
was followed, but this worm species is that recommended in the current
guidances, and the measured parameters are considered in the OPPTS
guideline; revealing they are relevant indicators of toxicity.
Hatchlings were exposed for 42 days to 50, 500, 2000 and 4000 mg/kg dw
of catechol. Mortality and growth were assessed. The first significant
effects were observed at 2000 and 4000 mg/kg dw for growth and
mortality, respectively. These values were thus retained as 42d-LOECs.
By deduction, the 42d-NOECs based on growth and mortality were 500 and
2000 mg/kg dw, respectively.
Based on Eisenia foetida survival: 42d-NOEC = 2000 mg/kg dw, 42d-LOEC = 4000 mg/kg dw.Based on Eisenia foetida growth: 42d-NOEC = 500 mg/kg dw, 42d-LOEC = 2000 mg/kg dw.
Only one reliable study is available
(Hartenstein, 1982). Despite it did not follow any guideline, it was
scored as a reliability 2 and flagged as a key study. Indeed, it was
fully described, the test species is that recommended in the current
guidances and the measured parameters are relevant indicators of
toxicity. Eisenia foetida hatchlings were exposed for 42 days to
catechol concentrations of 50, 500, 2000 and 4000 mg/kg dw. Based on
mortality, catechol presented 42d-NOEC and -LOEC of 2000 and 4000 mg/kg
dw. Based on growth, catechol presented 42d-NOEC and -LOEC of 500 and
2000 mg/kg dw.
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