Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.009 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor

Marine water

Hazard assessment conclusion:
no data: aquatic toxicity unlikely

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
3.21 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.007 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.001 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
0.002 mg/kg soil dw
Extrapolation method:
equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

The influence of the test item 3 -mercaptopropionic acid on aquatic organisms representing three different trophic levels was investigated in three acute studies in accordance with OECD guidelines and GLP principles. The acute toxicity determined was as follows: Brachydanio rerio 96 h-LC50 = 98 mg/L, Daphnia magna 48 h-EC50 = 9 mg/L, and Selenastrum capricornutum 72 h-ErC50 = 26 mg/L. In conclusion, the aquatic invertebrate Daphnia magna was the most sensitive organism tested with a 48 h-EC50 of 9 mg/L.

Furthermore, inhibitory effects on the respiration of activated sludge were also tested in a OECD guideline study under GLP. The study resulted in a 3 h-EC50 of 393.3 mg/L. The 3 h-EC10 was determined to be 32.1 mg/L.

Conclusion on classification

Potential threats of 3 -mercaptopropionic acid to the aquatic environment were determined in different ecotoxicological studies using different test species. All studies are conclusive and the results do not lead to a classification.