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EC number: 203-537-0 | CAS number: 107-96-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008.01.05-2008.04.24
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- other substance amounts and equilibration times used
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Swiss Federal Office of Public Health, Consumer protection directorate, Notification Authority for Chemicals, 3003 Bern, Switzerland
- Type of method:
- other: simplified flask method
- Water solubility:
- > 603.7 g/L
- Temp.:
- 20 °C
- pH:
- ca. 1.8
- Details on results:
- Two measurements of water solubility of 3-Mercaptopropionic Acid at room temperature were performed and values 618,9 and 588.4 g/L were recorded. Water solubility was found to be more than 603.7 g/L (mean value from two measurements according to HPLC measurements within the study). Because it was not possible to prepare a saturated solution, the water solubility might be higher than determined in the present study. The water solubility was not corrected for the purity of the test item.
- Executive summary:
Water solubility has been determined to be more than 603.7 g/L by using the simplified flask method. The study followed the procedures indicated by OECD Guideline No. 105 "Water solubility" and EEC Directive 92/69 (Method A.6 "Water solubility"). Based on the high solubility found in the preliminary test a main test as described in the guideline was not performed.
Reference
Description of key information
Water solubility: >=603.7 g/L at room temperature
Key value for chemical safety assessment
- Water solubility:
- 604 g/L
- at the temperature of:
- 20 °C
Additional information
Study performed in experimental laboratory (Franke, 2008, RCC) dedicated to estimate water solubility of the test material 3-Mercaptopropionic Acid has been chosen as a key study. Water solubility has been determined to be more than 603.7 g/L by using the simplified flask method. The study followed the procedures indicated by OECD Guideline No. 105 "Water solubility" and EEC Directive 92/69 (Method A.6 "Water solubility"). Based on the high solubility found in the preliminary test a main test as described in the guideline was not performed.
Another study (Rampy, 1973, Dow) qualitatively supports the result obtained in the key study and reports complete solubility of test substance in water.
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