Registration Dossier
Registration Dossier
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EC number: 203-537-0 | CAS number: 107-96-0
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient data to determine reliability
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Unpublished data Eastman Kodak.
- Author:
- Fassett, D.W.
- Year:
- 1 963
- Bibliographic source:
- Summarized in Patty's Industrial Hygiene and Toxicology |2nd Ed. Interscience Publishers, New York, New York.
Materials and methods
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-mercaptopropionic acid
- EC Number:
- 203-537-0
- EC Name:
- 3-mercaptopropionic acid
- Cas Number:
- 107-96-0
- Molecular formula:
- C3H6O2S
- IUPAC Name:
- 3-sulfanylpropanoic acid
- Details on test material:
- IUCLID4 Test substance: as prescribed by 1.1 - 1.4
Constituent 1
Test animals
- Species:
- guinea pig
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Vehicle:
- water
Results and discussion
Any other information on results incl. tables
RS-Freetext:
Neat material appears to be absorbed directly through the
guinea pig skin with deaths from as low as 5 ml/kg. Severe
delayed eschar formation was noted.
A 10% solution in water applied as a compress to guinea pig
skin produces severe damage and eschar. No deaths were
produced at this concentration.
No additional information provided.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
