Registration Dossier
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EC number: 203-537-0 | CAS number: 107-96-0
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Effect on fertility: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 88.3 mg/kg bw/day
Effect on fertility: via inhalation route
- Endpoint conclusion:
- no study available
Effect on fertility: via dermal route
- Endpoint conclusion:
- no study available
Additional information
The reproductive NOAEL for the methyl ester of 3-mercaptopropionic acid (MMP) is 100 mg/kg/d. The MW of 3-mercaptopropionic acid (3-MPA) corresponds to 88.3% of the MW of MMP. The NOAEL is accordingly corrected to 88.3 mg/kg/d.
Short description of key information:
No effects on fertility were noted in a screening study conducted according to OECD TG 422 with the methyl ester of 3-mercaptopropionic acid.
Effects on developmental toxicity
Description of key information
No effects on pre-natal development were noted in a screening study conducted according to OECD TG 422 with the methyl ester of 3-mercaptopropionic acid.
Effect on developmental toxicity: via oral route
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 88.3 mg/kg bw/day
Effect on developmental toxicity: via inhalation route
- Endpoint conclusion:
- no study available
Effect on developmental toxicity: via dermal route
- Endpoint conclusion:
- no study available
Additional information
The developmental NOAEL of the methyl ester of 3-mercaptopropionic acid (MMP) is 100 mg/kg/d. The MW of 3-mercaptopropionic acid (3-MPA) corresponds to 88.3% of the MW of MMP. The NOAEL is accordingly corrected to 88.3 mg/kg/d.
Justification for classification or non-classification
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