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Physical & Chemical properties

Partition coefficient

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partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance to national standard methods.
equivalent or similar to guideline
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
Type of method:
shake-flask method to: flask method
Partition coefficient type:
Specific details on test material used for the study:
Supplier: Tokyo Kasai Co
Analytical method:
other: gas-liquid chromatography with flame ionization detection
Key result
log Pow
Partition coefficient:
20 °C
ca. 7
Remarks on result:
other: pH determinations are not reported.
Details on results:
Value is the mean of four determinations.
The octanol-water partition coefficient was determined to be 0.97 at 20 deg C.
Executive summary:

Th octanol-water partition coefficient was tested OECD 107 (shake flask method)  and determined to be 0.97 at 20 °C.

Description of key information

The log Kow of HPMA is 0.97 (OECD Guideline 117/EU Method A.8; HPLC method).

Key value for chemical safety assessment

Log Kow (Log Pow):
at the temperature of:
20 °C

Additional information