Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
cytotoxicity
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Test procedure in accordance with generally accepted scientific standards and described in sufficient detail.

Data source

Reference
Reference Type:
publication
Title:
Cytotoxic effects of acrylates and methacrylates: Relationships of monomer structures and cytotoxicity;
Author:
Yoshii E.
Year:
1997
Bibliographic source:
J. Biomed. Mater. Res. 37(4): 517 - 524

Materials and methods

Test material

Results and discussion

Any other information on results incl. tables

The Cytotoxic effect of HPMA on the relative cell viability
of HeLa S3 cells was IC50: 8.67 mmol/L (50 % depression of
MTT-formazan production).

Applicant's summary and conclusion