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Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only summary English. Italian study.

Data source

Reference
Title:
No information
Author:
Corrao C.R.N., Cristaudo A., Carbone G., Sparano A.,|Santucci B., Ippolito F.; Occupational dermatitis in the|manufacture of contact lenses; Arch. Scienze Lav. 10: |233 - 236 (1994)

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Methacrylic acid, monoester with propane-1,2-diol
EC Number:
248-666-3
EC Name:
Methacrylic acid, monoester with propane-1,2-diol
Cas Number:
27813-02-1
Molecular formula:
C7H12O3
IUPAC Name:
1-hydroxypropan-2-yl 2-methylprop-2-enoate; 2-hydroxypropyl 2-methylprop-2-enoate

Results and discussion

Any other information on results incl. tables

RS-Freetext:
Results revealed a positive reaction to acrylic compounds in
5.5 % of subjects working at polishing and final control
operations.

Applicant's summary and conclusion