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Vapour pressure

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vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
EU Method A.4 (Vapour Pressure)
Version / remarks:
[Directive 92/69/EEC, Official Journal L 383 A 1992]
according to guideline
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
adopted on 27 July 1995
GLP compliance:
Type of method:
dynamic method
Specific details on test material used for the study:
- Name of test material (as cited in study report): 2-Hydroxypropylmethacrylat (CAS: 27813-02-1)
Supplier: Röhm GmbH & Co. KG
Purity: 99.05 % (GC, Röhm: M2-9)
PPG-MA: 0.395 % (GC, Röhm: M2-9)
PGDMA: 0.018 % (GC, Röhm: M2-9)
Water: 255 ppm (Karl-Fischer, Röhm: M3)
Inhibitor: HQME 216 ppm (HPLC, Röhm: M1-12)
Key result
20 °C
Vapour pressure:
0.11 hPa
Remarks on result:
other: Calculated by mathmatical extrapolation

Up to 120 °C the sample boiled intermittendly, above 160 °C the sample foamed. Measurements after cooling the sample  were not possible due to  polymerization. Thus only the data points above 120 °C were used for the  calculation.

Vapor pressure       Boiling temp.     Inverse temp.
    [hPa]              [°C]             * 1000
    8.2                90.6             2.7491
   15.4                99.8             2.6813
   31.1               111.7             2.5984
   53.4               123.2             2.5230
   99.3               137.7             2.4340
  202.8               156.3             2.3286
  349.9               172.4             2.2444
  500.6               183.4             2.1903
  753.1               198.5             2.1202
  992.1               209.9             2.0702

The vapor pressure was determined to be 0.11 hPa at 20 deg C.
Executive summary:

The vapour pressure of hydroxypropyl methacrylate was measured by dynamic method acc. OECD 104 and extrapolated to 20 °C. The vapor pressure was calculated to be 0.11 hPa at 20 deg C.

Description of key information

The vapour pressure of HPMA is 0.11 hPa at 20°C (OECD guideline 104/EU test method A.4; dynamic method).

Key value for chemical safety assessment

Vapour pressure:
0.11 hPa
at the temperature of:
20 °C

Additional information

The test result is confirmed by the calculated vapour pressure of hydroxypropyl methacrylate with EPI Suite 4.1. The calculated mean vapour pressure acc. Antoine & Grain method is 0.057 hPa @ 25 °C based on a measured boiling point of 209 °C (Röhm 2007).