Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Additional toxicological data

Currently viewing:

Administrative data

additional toxicological information
Adequacy of study:
other information
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only summary of the studies available. No details.

Data source

No information
Rohm & Haas, personal communication (1994), unpublished|report, Rohm & Haas, No. 91RC-197B (1991)

Materials and methods

Type of study / information:
Type: adsorption

Test material

Results and discussion

Any other information on results incl. tables

Dermal absorption was studied in male rats receiving 50 ul
of a 2000 ppm solution of 14C HPMA in engine oil. Exposure
time was 8 hours.
Total recovery of 14C: 81 %. 56 % evaporated from the dosing
site. The amount absorbed was determined to be 29 % of the
radioactivity. Radioactivity was observed in the skin (7 %),
carcass (2 %), urine (1 %), faeces (< 1 %) and as volatile
organics (< 1 %).

Applicant's summary and conclusion