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EC number: 200-543-5
CAS number: 62-56-6
66 female sheep (18 growing lambs, 18 maiden ewes, 9 pregnant ewes;
controls: 9 growing lambs, 9 maiden ewes, 3 pregnant ewes) were
administered orally 0 and 50 mg thiourea/kg body weight daily for 2, 4,
or 6 month. External genitalia were infantile and stunted in growing
lambs and pale anaemic and dry in maiden ewes. The growing lambs did not
show signs of estrus and mammary development was retarded. Thiourea
administered to pregnant ewes induced abortion, stillbirth, birth of
weak/low-weight lambs, dystokia, and retention of placenta. The severity
of changes was dependent upon the stage of gestation when hypothyroidism
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