Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-543-5
CAS number: 62-56-6
There are two different sources of information available which are used in a weight-of-evidence approach. In the CRC Handbook of Chemistry and Physics the dissociation constant of thiourea at 25 °C is stated to be pKa = –1. Data on the determination dissociation constant according OECD guideline 112 of the sponsor showed that pka-value is not determinable because Thiourea forms no OH or H ions.
According the CRC Handbook of Chemistry and physics
the dissociation constant of thiourea at 25 °C is pKa = –1.
In another study provided by the sponsor the
dissociation constant of Thiourea was determined according to OECD
guideline no. 112 with the titration method at 24 °C. It was shown that
the pka-value was not determinable because Thiourea forms no OH or H ions.
This study is chosen as key value as an experimental result has a higher
reliability than handbook data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again