Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-543-5
CAS number: 62-56-6
Reliable studies (Klimisch score 1 or 2)
that can be used in the assessment of the bioaccumulation potential of
thiourea are not available. Nonetheless, a new bioaccumulation study in
aquatic species does not need to be conducted, as in accordance with
column 2 of REACH Annex IX the substance has a low potential for
bioaccumulation (log octanol water partition coefficient less than 3).
This statement is further supported by two
Klimisch 3 studies conducted by Geyer et al. (1984) and Freitag et al.
- Geyer et al. (1985) exposed algae
(Chlorella) to 14C-labelled thiourea for at least 24 h at room
temperature (20-25 °C). The bioaccumulation factor for the alga
Chlorella was determined to be 54.
- Freitag et al. (1985) experimentally
determined the bioconcentration of thiourea in the fish Leuciscus
idus melanotus after 3 days of exposure to be < 10.
Due to the information and results presented
above, it can be concluded that thiourea does not have a significant
potential for bioaccumulation. Following the precautionary principle the
higher BCF value of 54 is used as key value in the risk assessment.
Data on terrestrial bioaccumulation are not
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Esta web utiliza cookies para mejorar su experiencia de navegación en nuestros sitios web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again