Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-543-5 | CAS number: 62-56-6
Endpoint summary
Administrative data
Description of key information
Thiourea is non-toxic to earthworms. Two 28-d studies on the toxicity toEisenia foetida(endpoint recorded: mortality) are available, reporting LC50values above 1000 mg/kg substrate (Korte & Freitag, 1984) and equal to 3,550 mg/kg substrate (Friesel et al., 1984), respectively.
Several plant species were tested in the plant toxicity assessment of thiourea. The most sensitive reliable EC50(10 d) of 52.1 mg/kg soil dw is reported by Günther & Pestemer (1990).
The toxicity of thiourea to soil microorganisms was investigated in several studies (Lashen & Starkey, 1970; Pandey et al. 1976; Zacherl & Amberger, 1990; Kubota & Asami, 1985). It could be shown that thiourea is toxic to soil microorganisms and inhibits growth as well as nitrification. Acclimatisation to thiourea occurs over time and thiourea can be decomposed.
Besides, five study abstracts were available for review that describe the chemosterilising effects of thiourea on beetles and flies (Shanker at al., 1990; Pandey & Pandey, 1991; Bhide, 1991; Chaudhry &Tripathi, 1976; Deepak & Chaudhry, 1979). The terrestrial invertebrates examined in these studies all live above-ground and are therefore outside the scope of REACH (see ECHA Guidance Document R.7c, p. 105). This information is of supplemental character only.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
