Registration Dossier
Registration Dossier
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EC number: 200-543-5 | CAS number: 62-56-6
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- no data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- according to guideline
- Guideline:
- other: no guideline reported
- GLP compliance:
- not specified
- Type of method:
- other: handbook data
- Water solubility:
- ca. 13.7 other: g /100 g
- Temp.:
- 20 °C
- Remarks on result:
- other: no data on pH available; handbook data
- Conclusions:
- Very soluble (> 10000 mg/L)
The water solubility of thiourea at 20°C is 13.7 g/ 100g water. - Executive summary:
The water solubility of thiourea is according the Ullmann`s Encyclopedia of Industrial Chemistry 13.7 g/ 100g water at 20°C which equates 137 g/l. Thus, thiourea is very soluble.
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- no data
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- yes
- Remarks:
- : pH of the samples was not determined
- Qualifier:
- according to guideline
- Guideline:
- other: OECD testguideline A80/6
- GLP compliance:
- not specified
- Type of method:
- flask method
- Water solubility:
- ca. 90 g/L
- Temp.:
- 20 °C
- Remarks on result:
- other: pH that relates to the value of the water solubility is not reported.
- Conclusions:
- Interpretation of results: soluble (1000-10000 mg/L)
The water solubility of thiourea is 90 g/l at 20°C. - Executive summary:
The water solubility of thiourea was determined at 20°C according the OECD testguideline A80/6 "Flask method" applying spectralphotometry. Thiourea is soluble. The water solubility is 90 g/l.
Referenceopen allclose all
Description of key information
There are four literature sources available for the weight of evidence.
The results indicate that thiourea is soluble (1000-10000mg/l) to very soluble in water (> 10000mg/l).
Key value for chemical safety assessment
- Water solubility:
- 137 g/L
- at the temperature of:
- 20 °C
Additional information
The data on the water solubility of thiourea of the Ullmann handbook is chosen for robust study summary because of the reference temperature of 20 °C instead of 25 °C.
According to four different literature sources thiourea is soluble (1000-10000 mg/l) to very soluble (> 10000mg/l) in water:
- 137.0 g/l at 20 °C (according to Ullmann, 1995)
- 90 g/l at 20 °C (according to Korte und Greim, 1981)
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