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EC number: 205-087-0
CAS number: 133-06-2
Analysis of solutions: Measured concentrations of captan in the stock
solutions ranged from 91 to 100% of the nominal values. The analytical
results are therefore calculated based on dilution of the stock solution
and the toxicity results are based on nominal values. The physical and
chemical parameters of the test solutions remained at expected values
during the study.
Toxicity, reproduction and body length: No symptoms other than mortality
and no dead offspring were observed. The results are summarised in Table
Table 6.1.4-1 Summary of
effects of captan on Daphnia magna following 21-day exposure
after 21 days
different from water and/or solvent control at P = 0.05.
Figures in parenthesis are %
of control values.
The chronic toxicity of
captan technical to Daphnia magna was determined. Due to the rapid
hydrolysis of captan in aqueous conditions the results have been
expressed as nominal concentrations. The
methods were based on those described In the relevant OECD method 202
(1984) equivalent to OECD 211, modified by individually separating the
The test organism was the
freshwater crustacean, Daphnia magna Straus, obtained from continuous
laboratory cultures at the ICI Group Environmental Laboratory. Daphnia
<24 hours old, obtained from a Single culture vessel, were used for
testing. Ten replicate vessels, each containing one Daphnia were
employed for the control, solvent control and each concentration of test
duration of the test was 21 days. There were no mortalities in the
control and nominal test concentrations of 0.32 and 0.56 mg/L after 21
days. In the solvent control and nominal concentration of 1.0 mg/L,
there was 10% mortality during the test. The 21-day EC50 of captan to
Daphnia magna under semi-static conditions was greater than 1.0 mg/L.
The mean number of offspring
produced by the control and solvent control were significantly different
(P = 0.05, t-test, one-sided). Therefore, the treatments were compared
with the solvent control only. The no observed effect concentration
(NOEC) for reproduction is 0.56 mg/L (nominal).
The length of the surviving P0
Daphnia at the end of the test at nominal concentrations up to and
including 0.56 mg/L mean length was not significantly reduced. Therefore
the no observed effect concentration (NOEC) for length is 0.56 mg/L
Long-term toxicity to aquatic invertebrates, 21-day, Daphnia magna under semi-static conditions: EC50 > 1.0 mg/L, NOEC = 0.56 mg/L (based on reduction in offspring and body length, OECD Guideline No 202 (1984) equivalent to OECD Guideline No 211 (1998)
Long-term toxicity to Daphnia was determined according to OECD 202
(1984) (similar to OECD 211 (1998)). Up to a concentration of 1.0 mg/L
captan no symptoms other than mortality and no dead offspring were
observed. The no observed effect concentration (NOEC) for reproduction
is 0.56 mg/L (nominal) due to significant offspring reduction in respect
to control groups at 1.0 mg/l concentration.
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