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EC number: 701-068-0
CAS number: 2156592-58-2
From a water-sediment Chironomid toxicity study using spiked sediment (OECD 218), a NOEC (28 d; emergence and development rate) of 188 mg/kg sediment dw was determined.
For assessment of sediment toxicity, read-across from supporting
substance C16-18(even numbered)-alkylamine acetate (CAS No.:
1273322-45-4) is carried out. In a reliable study (RL 1) performed
compliant with GLP according to OECD 218 (Noack, Study-No.: IZS15732),
toxicity of the test item spiked into sediment towards Chironomus larvae
was investigated. The NOEC (28 days) for both, emergence rate as well as
development rate was determined to be 188 mg/kg sediment dry weight.
Comparison of the LOEC (28 d; 455 mg/kg sediment dry weight) with the
EC50 (mortality, 28 d; 412 mg/kg sed. dw) demonstrates that there is no
specific action of the primary amine with regard to endpoints
development and emergence.
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