Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-068-0
CAS number: 2156592-58-2
With regard to mutagenicity, only negative results were obtained for
primary alkylamines in both, in vitro and in vivo. C12 -18 -(even
numbered)-alkylamines have been shown to be not mutagenic in bacterial
gene mutation testing. Likewise only negative results from tests on
bacterial mutagenicity and data on gene and chromosome mutations in
mammalian cells in vitro and on chromosomal aberrations and micronuclei
in vivo were revealed for the whole category of primary alkylamines.
Alltogether, the negative data are considered as sufficient to exclude a
mutagenic potential of C12 -18 -(even numbered)-alkylamines in vivo.
This conclusion is in line with the existing EU risk assessment on
primary alkylamines in general.
Based on the available database confirming the absence of a mutagenic
potential in vitro as well as in vivo, respective classification of C12
-18 -(even numbered)-alkylamines, as well as of the whole category of
primary alkylamines, is not warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again