Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-068-0
CAS number: 2156592-58-2
There are no valid human data available on sensitization for either the
C12 -18 -(even numbered)-alkylamines, nor for any other of the primary
alkylamines considered a chemical category within this chemical safety
assessment. Animal data exist on C12 -18 -(even numbered)-alkylamines
from a GLP-compliant Magnusson and Kligman maximisation test which
demonstrated absence of a significant skin sensitizing potential, as
well as from a non-GLP M+K maximisation test with hydrogenated tallow
alkylamines which resulted also in an negative outcome. From both
studies no significant skin sensitization potential of primary
alkylamines is deducible. Additionally, since all primary alkylamines
exhibite strong dermal irritative / corrosive properties, dermal
exposure has to be limited anyway.
negative skin sensitization data available for C12 -18 -(even
numbered)-alkylamines as well as for other primary alkylamines, a
respiratory sensitization potential of hydrogenated tallow alkylamines
is not to be expected. Due to the corrosive nature of
C12-18-(even numbered)-alkylamines additional testing is not warranted.
C12 -18 -(even numbered)-alkylamines does not fulfill the requirements
for classification as skin and/or respiratory sensitizer. A maximization
test according to Magnusson and Kligman has not revealed significant
skin sensitizing properties. Additionally C12 -18 -(even
numbered)-alkylamines, like most of the alkylamines considered a
chemical category, is corrosive to skin and classified as R35 - causes
severe burns. Based hereupon, any potential dermal exposure has to be
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again