Registration Dossier
Registration Dossier
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EC number: 202-423-8 | CAS number: 95-48-7
Additional toxicological data
Administrative data
- Endpoint:
- additional toxicological information
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: in vitro investigation, reliablility of limited relevance
Data source
Referenceopen allclose all
- Title:
- No information
- Author:
- Curvall M et al. (1984). An evaluation of the utility of four in vitro short term tests for predicting the cytotoxicity of individual compounds derived from tobacco smoke. Cell Biol. Toxocl. 1, 173-193
- Title:
- No information
- Author:
- Pettersson B et al.(1982). Effects of tobacco smoke compounds on the cilliary activity of the embryo chicken trachea in vitro. Toxicology 23, 41-55
Materials and methods
- Type of study / information:
- Type: other: in vitro
Test material
- Reference substance name:
- o-cresol
- EC Number:
- 202-423-8
- EC Name:
- o-cresol
- Cas Number:
- 95-48-7
- Molecular formula:
- C7H8O
- IUPAC Name:
- o-cresol
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Executive summary:
Ciliostasis within 15 min was observed when 5mM o-cresol was added to embryo chicken trachea in culture.
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