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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: in vitro investigation, reliablility of limited relevance

Data source

Referenceopen allclose all

Title:
No information
Author:
Curvall M et al. (1984). An evaluation of the utility of four in vitro short term tests for predicting the cytotoxicity of individual compounds derived from tobacco smoke. Cell Biol. Toxocl. 1, 173-193
Title:
No information
Author:
Pettersson B et al.(1982). Effects of tobacco smoke compounds on the cilliary activity of the embryo chicken trachea in vitro. Toxicology 23, 41-55

Materials and methods

Type of study / information:
Type: other: in vitro

Test material

Constituent 1
Chemical structure
Reference substance name:
o-cresol
EC Number:
202-423-8
EC Name:
o-cresol
Cas Number:
95-48-7
Molecular formula:
C7H8O
IUPAC Name:
o-cresol

Results and discussion

Applicant's summary and conclusion

Executive summary:

Ciliostasis within 15 min was observed when 5mM o-cresol was 
added to  embryo chicken trachea in culture.

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