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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The toxicity of o-cresol to the blue-green algae Microcystis aeruginosa (Cyanaophyceae) was determined in a cell multiplication inhibition test according to the guideline DEV L9. The relevant 8d-NOEC (EC3) is 6.8 mg/L .

Key value for chemical safety assessment

EC10 or NOEC for freshwater algae:
6.8 mg/L

Additional information

Concerning toxicity to aquatic algae there are several tests towards various species using o-cresol as test substance available.

The lowest toxicity value obtained with a blue-green algae is taken into account for further assessment.

The toxicity of o-cresol to the blue-green algae Microcystis aeruginosa (Cyanaophyceae) was determined in a cell multiplication inhibition test according to the guideline DEV L9. Test conditions were as follows: continuous light, 27°C, with or without neutralization. The pH of the neutralized test solution was 7. For the endpoint biomass at the end of the test an 8 day-toxicity threshold value of 6.8 mg/l was obtained (nominal concentration). This toxicological threshold can also be regarded as a NOEC- or an EC3-value. For this reason the NOEC value can be given as 6.8 mg/l.

With a growth inhibition test according to a dutch national standard method NEN-6506 (1980) on alga Selenastrum sp. a 96-hour EC50 of 100 mg/L based on nominal concentrations was determined for o-cresol.

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