Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Biodegradation behaviour of o-cresol was assessed in several experiments showing that the substance is readily as well as inherently biodegradable in water and soil.

Primary metabolic intermediates of o-cresol using phenol-adapted activated sludge were 3 -methylcatechol, 4 -methylresorcinol and methylhydroquinone. Secondary degradation products are formed either by further hydroxylation yielding trihydroxy and tetrahydroxy-toluenes or by cleavage of the aromatic ring system.

Aerobic degradation experiments in soil yielding a half-life times of 1.6 d for the sandy loam (basic soil) and 5.1 d for the sandy silt loam (acidic soil).

No anaerobic degradation was observed in primary anaerobic sludges from 12 treatment plants receiving mainly domestic wastewater.

o-cresol is readily biodegradable under aerobic conditions. Therefore, if released to wastewater or surface water, it is unlikely that o-cresol will reach the anaerobic zones. Anaerobic degradation is expected to be of minor importance for the hazard assessment of o-cresol.