Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information


The tropospheric half-life of o-cresol is approximately 9 h due to degradation by OH radicals with an average concentration of 500000 radicals/mL.

With regard to its chemical structure o-cresol is not expected to hydrolyses under environmental conditions.


o-Cresol is readily biodegradable. It is inherent biodegradable, but not anaerobically biodegradable..

Biodegradation half-lives in 2 agricultural soils were determined to be 1.6 for a sandy loam and 5.1 for a sandy silt loam.


In a flow-through test according to the OECD guideline 305 E a BCF of 10.7 in zebrafish (Brachydanio rerio) was obtained for o-cresol, indicating that the substance is not bioaccumulative.

Adsorption / desorption

The Koc of o-cresol was determined in an experiment, similar to the OECD Guideline 106. Koc values of 22 - 56 for different soils and sediments were obtained, suggesting a low potential for adsorption.


The experimentally determined Henry's law constant for o-cresol is 0.15 Pa*m³/mole at 25°C.

The distribution of o-cresol in a unit world was calculated according to the Mackay fugacity model level I based on its physico-chemical properties. The main target compartment for o-cresol is water with 93.7 %, followed by air with 5 %, soil and sediment each with 0.7 %.