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Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 

Further information

 

For more information on these substances, please go to
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Page 25 of 41
50 Items per Page
Showing 1,201 - 1,250 of 2,011 results.
Name
EC Number
CAS Number
Hazard endpoint for which vertebrate testing was proposed
Date of publication to call for available information
Deadline for submitting information
Alternatives to vertebrate testing
 
Methyl benzoylformate 239-263-3 15206-55-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/10/2022
26/10/2022
12/12/2022
12/12/2022
 Details
1,6-Bis((dibenzylthiocarbamoyl)disulfanyl)hexane 429-280-6 151900-44-6 Reproductive toxicity (developmental toxicity) 01/09/2010 15/10/2010 Details
A mixture of isomers of branched tetracosane 417-060-2 151006-61-0
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 1-decene, dimer (EC 917-709-4), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)
01/07/2021
01/07/2021
01/07/2021
16/08/2021
16/08/2021
16/08/2021
 Details
1-Dodecene, dimer with 1-decene, hydrogenated 604-766-2 151006-58-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-decene, dimer (EC 917-709-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-Dodecene, Dimer (EC 814-509-8) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and 1-Dodecene, dimer, hydrogenated (EC 604-768-3)
01/07/2021
01/07/2021
01/07/2021
16/08/2021
16/08/2021
16/08/2021
 Details
Aziridine 205-793-9 151-56-4 Long-term toxicity to fish 26/01/2011 14/03/2011 Details
a,a-dimethylphenethyl acetate 205-781-3 151-05-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2017
17/05/2017
03/07/2017
03/07/2017
 Details
Mequinol 205-769-8 150-76-5 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2011 14/06/2011 Details
Dichloro(methyl)(phenyl)silane 205-746-2 149-74-6 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Trimethoxy(phenyl)silane (EC 221-066-9, CAS 2996-92-1) 04/04/2014 19/05/2014 Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2011
15/04/2011
15/04/2011
30/05/2011
30/05/2011
30/05/2011
 Details
Sodium hydroxymethanesulphinate 205-739-4 149-44-0 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019 Details
bismuth oxide salicylate 238-953-1 14882-18-9 Sub-chronic toxicity (90 day): oral || Note: testing proposed with bismuth hydroxide nitrate oxide (EC 215-136-8) 18/09/2014 03/11/2014 Details
Ethylenediamine, salt with phosphoric acid 238-914-9 14852-17-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 27/01/2020 12/03/2020 Details
3-(triethoxysilyl)propanethiol 238-883-1 14814-09-6
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/10/2014
16/10/2014
16/10/2014
01/12/2014
01/12/2014
01/12/2014
 Details
4,4'-[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]diphenol; bisphenol AF 216-036-7 1478-61-1 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
2-Oxetanone, 3-C12-16-alkyl-4-C13-17-alkylidene derivs., (4E)- 939-401-9 1469983-41-2 Long-term toxicity to fish ||Note: testing proposed with 2-Oxetanone, 3-C14-16-alkyl 4-C15-17-alkylidene derivs (EC no. 308-760-8) 15/07/2022 29/08/2022 Details
Hexanoic acid, 3,5,5-trimethyl-, 2,2,6,6-tetramethyl-1-[2-[(3,5,5-trimethyl-1-oxohexyl)oxy]ethyl]-4-piperidinyl ester 941-267-1 1445870-18-7
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2023
31/01/2023
31/01/2023
17/03/2023
17/03/2023
17/03/2023
 Details
N,N-dimethyldecan-1-amide 238-405-1 14433-76-2 Long-term toxicity to fish 15/07/2011 29/08/2011 Details
2,2,4-trimethylpentane-1,3-diol 205-619-1 144-19-4 Reproductive toxicity (pre-natal developmental toxicity) 18/02/2014 04/04/2014 Details
Zinc bis(diethyldithiocarbamate) 238-270-9 14324-55-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 10/08/2018 24/09/2018 Details
Bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 26/03/2018 11/05/2018 Details
bis(2-(2-butoxyethoxy)ethoxy)methane 205-598-9 143-29-3
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
15/04/2011
15/04/2011
30/05/2011
30/05/2011
 Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity):
1st PNDT on the registered substance
2nd PNDT with the registered substance
// Note: Testing proposal for an EOGRTS proposed to be conducted with the analogue substance 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1, CAS 112-35-6) 		27/01/2020 12/03/2020 Details
2-(2-(2-butoxyethoxy)ethoxy)ethanol 205-592-6 143-22-6 Reproductive toxicity (pre-natal developmental toxicity) 10/08/2018 24/09/2018 Details
Lithium tetrafluoroborate, anhydrous 238-178-9 14283-07-9 Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
Alcohols, C6-8, ethoxylated 800-182-9 1426148-68-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/11/2022
28/11/2022
12/01/2023
12/01/2023
 Details
sodium/triethanolamine 4-((2-hydroxyethyl)amino)-3-pentaproenyl-4-oxobutanoate 800-765-8 1424149-03-0 Reproductive toxicity (pre-natal developmental toxicity) 15/07/2014 29/08/2014 Details
Dodecyl methacrylate 205-570-6 142-90-5 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
Fatty acids, tall-oil, reaction products with fatty acids C16-C18 and C18-unsatd, branched and linear, diethylenetriamine and maleic anhydride 806-508-6 1419212-77-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral Note: testing proposed with substance Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride (CAS: 1419212-76-2)
05/06/2014
05/06/2014
21/07/2014
21/07/2014
 Details
Fatty acids, tall-oil, reaction products with diethylenetriamine and maleic anhydride 800-430-6 1419212-76-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
05/06/2014
05/06/2014
21/07/2014
21/07/2014
 Details
(3E)-2-chloro-3-(hydroxymethylene)cyclohexene-1-carbaldehyde 801-656-8 1416808-92-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 17/04/2015 04/06/2015 Details
O-isopropyl ethylthiocarbamate 205-517-7 141-98-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): oral
16/05/2014
16/05/2014
30/06/2014
30/06/2014
 Details
dodecamethylpentasiloxane 205-492-2 141-63-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
17/06/2020
17/06/2020
03/08/2020
03/08/2020
 Details
dodecamethylpentasiloxane 205-492-2 141-63-9 Reproductive toxicity (pre-natal developmental toxicity)
Note: testing proposed with Decamethyltetrasiloxane (EC 205-491-7). 		25/06/2015 10/08/2015 Details
decamethyltetrasiloxane 205-491-7 141-62-8 Reproductive toxicity (pre-natal developmental toxicity) 16/10/2014 01/12/2014 Details
Trichloro(propyl)silane 205-489-6 141-57-1 Reproductive toxicity (pre-natal developmental toxicity) // Note: testing proposed with Triethoxy(propyl)silane (EC 219-842-7, CAS 2550-02-9) 04/04/2014 19/05/2014 Details
Bis(2-butoxyethyl) adipate 205-466-0 141-18-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
Bis(2-ethylhexyl) fumarate 205-448-2 141-02-6
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
 Details
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate 925-259-5 140921-24-0
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/05/2014
16/05/2014
16/05/2014
30/06/2014
30/06/2014
30/06/2014
 Details
1,6-hexanediyl-bis(2-(2-(1-ethylpentyl)-3-oxazolidinyl)ethyl)carbamate 411-700-4 140921-24-0
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
10/05/2022
10/05/2022
10/05/2022
27/06/2022
27/06/2022
27/06/2022
 Details
potassium tetrafluoroborate 237-928-2 14075-53-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90 day): inhalation
02/06/2014
02/06/2014
17/07/2014
17/07/2014
 Details
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene 801-941-7 1404190-37-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/05/2016
31/05/2016
15/07/2016
15/07/2016
 Details
((3-(sec-butyl)-4-(decyloxy)phenyl)methanetriyl)tribenzene 801-941-7 1404190-37-9
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/10/2016
20/10/2016
05/12/2016
05/12/2016
 Details
Morpholine, 4-C12-14-alkyl derivs. 800-906-3 1402434-48-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
04/04/2014
04/04/2014
 Details
Cobalt(II) 4-oxopent-2-en-2-olate 237-855-6 14024-48-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
 Details
Cobalt(II) 4-oxopent-2-en-2-olate 237-855-6 14024-48-7
"Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4) || Note: Testing proposal is based on concern identified by the registrant. "
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) || Note: Testing proposal is based on concern identified by the registrant.
21/09/2020
21/09/2020
05/11/2020
05/11/2020
 Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8
Chronic toxicity/carcinogenicity
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
14/02/2011
14/02/2011
14/02/2011
31/03/2011
31/03/2011
31/03/2011
 Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Sub-chronic toxicity (90-day): oral 21/10/2011 05/12/2011 Details
2-piperazin-1-ylethylamine 205-411-0 140-31-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
Potassium dicyanoaurate 237-748-4 13967-50-5 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 17/06/2020 03/08/2020 Details
hexahydrophthalic acid diglycidylester 696-026-0 1395383-69-3 Sub-chronic toxicity (90-day): oral 16/10/2014 01/12/2014 Details
Page 25 of 41
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Showing 1,201 - 1,250 of 2,011 results.