Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

Showing 801 - 850 of 2,011 results.

Name	EC Number	CAS Number	Hazard endpoint for which vertebrate testing was proposed	Date of publication to call for available information	Deadline for submitting information
Sodium hydrogen N-(1-oxotetradecyl)-L-glutamate	253-981-4	38517-37-2	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with L-Glutamic acid, N-coco acyl derivs., disodium salts (CAS number: 68187-30-4; EC number: 269-085-1) \|\| Note: Testing proposal is based on concern identified by the registrant.	17/12/2019	31/01/2020	Details
bis(3,5,5-trimethylhexanoyl) peroxide	223-356-0	3851-87-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts	609-542-8	383178-66-3	Reproductive toxicity (pre-natal developmental toxicity)	30/11/2015	14/01/2016	Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with 3-aminomethyl-3,5,5-trimethylcyclohexylamine	500-101-4	38294-64-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/04/2014 15/04/2014	30/05/2014 30/05/2014	Details
2-Propyn-1-ol, compd. with methyloxirane	609-530-2	38172-91-7	Sub-chronic toxicity (90-day): oral	16/10/2014	01/12/2014	Details
4,4'-[(isopropylidene)bis(p-phenyleneoxy)]diphthalic dianhydride	253-781-7	38103-06-9	Sub-chronic toxicity (90-day): oral	27/01/2020	12/03/2020	Details
2-phosphonobutane-1,2,4-tricarboxylic acid	253-733-5	37971-36-1	Long-term toxicity to fish\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3) Reproductive toxicity (pre-natal developmental toxicity)\|\|Note: testing proposed with Tetrasodium hydrogen 2-phosphonatobutane-1,2,4-tricarbolxyate, (EC No. 266-442-3)	26/10/2022 26/10/2022	12/12/2022 12/12/2022	Details
2-Oxepanone, polymer with 2-ethyl-2-(hydroxymethyl)-1,3-propanediol	500-099-5	37625-56-2	Reproductive toxicity (pre-natal developmental toxicity)	15/07/2011	29/08/2011	Details
2,4-Pentanedione, peroxide	253-384-9	37187-22-7	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	30/11/2015 30/11/2015	14/01/2016 14/01/2016	Details
Octa-1,7-diene	223-054-9	3710-30-3	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	18/02/2014 18/02/2014	04/04/2014 04/04/2014	Details
(E)-1,1,1,2,3,4,5,5,5-Nonafluoro-4-(trifluoromethyl)pent-2-ene	807-113-1	3709-71-5	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90 day): inhalation	19/10/2020 19/10/2020	03/12/2020 03/12/2020	Details
2-Oxepanone, polymer with 1,6-hexanediol	609-271-5	36609-29-7	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with 2-Oxepanone, polymer with 1,4-butanediol	16/10/2014 16/10/2014	01/12/2014 01/12/2014	Details
2,2-dimethylpropan-1-ol, tribromo derivative	253-057-0	36483-57-5	Reproductive toxicity (pre-natal developmental toxicity)	17/04/2015	04/06/2015	Details
Diundecyl phthalate	222-884-9	3648-20-2	Reproductive toxicity (pre-natal developmental toxicity)	25/11/2021	10/01/2022	Details
Dioctyltin dilaurate	222-883-3	3648-18-8	Reproductive toxicity (pre-natal developmental toxicity)	23/03/2020	07/05/2020	Details
4,4'-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with maleic anhydride and methacrylic acid	500-090-6	36425-16-8	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with a structurally related substance (small vinyl ester) Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with a structurally related substance (small vinyl ester)	31/05/2016 31/05/2016	15/07/2016 15/07/2016	Details
4,4`-Isopropylidenediphenol, oligomeric reaction products with 1-chloro-2,3-epoxypropane, reaction products with methacrylic acid	500-089-0	36425-15-7	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	01/07/2011 01/07/2011 01/07/2011	15/08/2011 15/08/2011 15/08/2011	Details
1,3-bis(isocyanatomethyl)benzene	222-852-4	3634-83-1	6.1.2 Long-term toxicity to fish	08/03/2024	22/04/2024	Details
N-butylbenzenesulphonamide	222-823-6	3622-84-2	Reproductive toxicity (pre-natal developmental toxicity)	14/02/2011	31/03/2011	Details
N-butylbenzenesulphonamide	222-823-6	3622-84-2	Reproductive toxicity (pre-natal developmental toxicity)	29/02/2016	14/04/2016	Details
N-butyl-2,2,6,6-tetramethylpiperidin-4-amine	252-899-6	36177-92-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): ora	07/10/2016 07/10/2016	21/11/2016 21/11/2016	Details
Phosphonium, tetrakis(hydroxymethyl)-, chloride (1:1), reaction products with 1-tetradecanamine and urea	436-230-7	359406-89-6	Sub-chronic toxicity (90-day): oral	06/03/2012	20/04/2012	Details
N,N''-propane-1,3-diylbis[N'-octadecylurea	252-667-4	35674-65-8	Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity)	29/03/2016	13/05/2016	Details
Triethoxy(2,4,4-trimethylpentyl)silane	252-558-1	35435-21-3	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates. Reproductive toxicity (extended one-generation reproductive toxicity study) \|\| Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)	28/02/2018 28/02/2018	16/04/2018 16/04/2018	Details
Triethoxy(2,4,4-trimethylpentyl)silane	252-558-1	35435-21-3	Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral	29/04/2011 29/04/2011	14/06/2011 14/06/2011	Details
Trinonyl benzene-1,2,4-tricarboxylate	252-552-9	35415-27-1	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	11/11/2016 11/11/2016	03/01/2017 03/01/2017	Details
Propanamide, 2-hydroxy-N,N-dimethyl-	609-066-0	35123-06-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	18/03/2021	03/05/2021	Details
Propanamide, 2-hydroxy-N,N-dimethyl-	609-066-0	35123-06-9	Reproductive toxicity (extended one-generation reproductive toxicity study)	21/10/2021	07/12/2021	Details
Sodium 2-[(2-aminoethyl)amino]ethanesulphonate	252-173-9	34730-59-1	Reproductive toxicity (pre-natal developmental toxicity)	29/04/2014	13/06/2014	Details
triethoxy(3-thiocyanatopropyl)silane	252-161-3	34708-08-2	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/10/2014 16/10/2014 16/10/2014	01/12/2014 01/12/2014 01/12/2014	Details
1-butylpyrrolidin-2-one	222-437-8	3470-98-2	Reproductive toxicity (extended one-generation reproductive toxicity study)	25/01/2022	11/03/2022	Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid	252-156-6	34690-00-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90-day): oral \|\| Note: Testing proposal is based on concern identified by the registrant.	20/05/2015 20/05/2015	06/07/2015 06/07/2015	Details
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid	252-156-6	34690-00-1	Reproductive toxicity (pre-natal developmental toxicity) \|\| Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP Sub-chronic toxicity (90-day): oral \|\| Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP	31/01/2018 31/01/2018	19/03/2018 19/03/2018	Details
1-imino-1H-isoindol-3-amine	222-426-8	3468-11-9	Genetic toxicity in vivo	18/03/2021	03/05/2021	Details
1-imino-1H-isoindol-3-amine	222-426-8	3468-11-9	Genetic toxicity in vivo	27/01/2020	12/03/2020	Details
tert-butyl α,α-dimethylbenzyl peroxide	222-389-8	3457-61-2	Long-term toxicity to fish \|\| Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates	16/03/2015	30/04/2015	Details
tert-butyl α,α-dimethylbenzyl peroxide	222-389-8	3457-61-2	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	15/07/2014 15/07/2014	29/08/2014 29/08/2014	Details
Tris(nitrato-O)nitrosylruthenium	252-068-8	34513-98-9	Genetic toxicity in vivo	01/07/2021	16/08/2021	Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide	252-046-8	34455-29-3	Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020	01/02/2021 01/02/2021	Details
Carboxymethyldimethyl-3-[[(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl)sulphonyl]amino]propylammonium hydroxide	252-046-8	34455-29-3	Long-term toxicity to fish	03/10/2023	17/11/2023	Details
1-(2-hydroxyethyl)pyrrolidin-2-one	222-359-4	3445-11-2	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	16/12/2020 16/12/2020 16/12/2020	01/02/2021 01/02/2021 01/02/2021	Details
1-(2-hydroxyethyl)pyrrolidin-2-one	222-359-4	3445-11-2	Reproductive toxicity (pre-natal developmental toxicity)	14/08/2014	28/09/2014	Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate	252-029-5	34443-12-4	Reproductive toxicity (extended one-generation reproductive toxicity study) Reproductive toxicity (pre-natal developmental toxicity)	21/01/2021 21/01/2021	08/03/2021 08/03/2021	Details
OO-tert-butyl O-(2-ethylhexyl) peroxycarbonate	252-029-5	34443-12-4	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	21/03/2014 21/03/2014 21/03/2014	05/05/2014 05/05/2014 05/05/2014	Details
trimethoxy(2,4,4-trimethylpentyl)silane	251-995-5	34396-03-7	Long-term toxicity to fish	26/10/2022	12/12/2022	Details
trimethoxy(2,4,4-trimethylpentyl)silane	251-995-5	34396-03-7	Sub-chronic toxicity (90-day): oral Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) "	25/06/2015	10/08/2015	Details
Bisisobutyryl peroxide	222-340-0	3437-84-1	Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	04/04/2014 04/04/2014 04/04/2014	19/05/2014 19/05/2014 19/05/2014	Details
tert-pentyl hydroperoxide	222-321-7	3425-61-4	Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral	07/10/2016 07/10/2016	21/11/2016 21/11/2016	Details
tert-pentyl hydroperoxide	222-321-7	3425-61-4	Genetic toxicity in vivo	21/03/2014	05/05/2014	Details
Oleic acid, compound with (Z)-N-octadec-9-enylpropane-1,3-diamine (2:1)	251-846-4	34140-91-5	Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity)	10/05/2022 10/05/2022	27/06/2022 27/06/2022	Details

Showing 801 - 850 of 2,011 results.

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