Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Sulphamidic acid 226-218-8 5329-14-6 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with ammonium sulphamate (pH consideration) 23/04/2018 07/06/2018 Details
Ditetradecyl peroxydicarbonate 258-436-4 53220-22-7
Reproductive toxicity (pre-natal developmental toxicity
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Details
Oligomerisation reaction products of glyoxal and urea 610-945-6 53037-34-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/03/2014
03/03/2014
17/04/2014
17/04/2014
Details
4,4'-methylenebis[N-sec-butylaniline] 226-122-6 5285-60-9 Bioaccumulation aquatic / sediment 27/01/2020 12/03/2020 Details
octyltrichlorosilane 226-112-1 5283-66-9 Sub-chronic toxicity (90-day): oral || Note: testing proposed with triethoxy(2,4,4-trimethylpentyl)silane (EC 252-558-1, CAS 35435-21-3) 25/06/2015 10/08/2015 Details
2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, phosphate 258-053-2 52628-03-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
Details
Bis(O,O-diisopropyl dithiophosphate)bis(cyclohexylamine) zinc 809-986-4 52585-16-7 Genetic toxicity in vivo 22/04/2021 07/06/2021 Details
Zinc, bis[O,O-bis(1-methylethyl) phosphorodithioato-.kappa.S]bis(cyclohexanamine)-, (T-4)- 809-986-4 52585-16-7 Genetic toxicity in vivo 18/06/2018 02/08/2018 Details
Sodium 3-(allyloxy)-2-hydroxypropanesulphonate 258-004-5 52556-42-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2014
29/04/2014
13/06/2014
13/06/2014
Details
Poly[oxy(methyl-1,2-ethanediyl)], α,α'-(2,2-dimethyl-1,3-propanediyl)bis[ω-hydroxy-] 610-848-9 52479-58-0 Sub-chronic toxicity (90-day): oral 18/09/2014 03/11/2014 Details
1,3,5-tris(2,3-dibromopropyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 257-913-4 52434-90-9
Long-term toxicity to fish
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
03/04/2023
03/04/2023
03/04/2023
22/05/2023
22/05/2023
22/05/2023
Details
Glycerol, propoxylated, esters with acrylic acid 500-114-5 52408-84-1 Sub-chronic toxicity (90-day): oral 22/11/2017 08/01/2018 Details
3-(diethylamino)-7-oxo-7H-[1]benzopyrano[3',2':3,4]pyrido[1,2-a]benzimidazole-6-carbonitrile 257-884-8 52372-36-8 Genetic toxicity in vivo 26/10/2022 12/12/2022 Details
4-[3-(1-naphthylamino)propyl]morpholine 226-033-2 5235-82-5 Genetic toxicity in vivo 19/10/2020 03/12/2020 Details
Etocrilene 226-029-0 5232-99-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
24/02/2020
24/02/2020
09/04/2020
09/04/2020
Details
N-[3-(dimethylamino)propyl]methacrylamide 226-002-3 5205-93-6 Reproductive toxicity (pre-natal developmental toxicity) 29/04/2011 14/06/2011 Details
5-ethyl-1,3-dioxane-5-methanol 225-967-8 5187-23-5
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2014
31/01/2014
17/03/2014
17/03/2014
Details
5-ethyl-1,3-dioxane-5-methanol 225-967-8 5187-23-5
Long-term toxicity to fish
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
03/10/2023
03/10/2023
03/10/2023
17/11/2023
17/11/2023
17/11/2023
Details
N-[2-[(2-bromo-4,6-dinitrophenyl)azo]-5-(diallylamino)-4-methoxyphenyl]acetamide 257-486-4 51868-46-3 Genetic toxicity in vivo 26/10/2022 12/12/2022 Details
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: testing proposed with dihydrogen hexahydroxyplatinate, compound with 2-aminoethanol (1:2) (EC 268-717-3) 21/12/2021 04/02/2022 Details
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018 Details
3,7-dimethyloct-6-enenitrile 257-288-8 51566-62-2 Reproductive toxicity (pre-natal developmental toxicity) 03/03/2014 17/04/2014 Details
2-(2-Ethoxyethoxy)-2-methylpropanee 257-196-8 51422-54-9 Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016 Details
cobalt carbonate 208-169-4 513-79-1
Carcinogenicity || Note: testing proposed with Cobalt dichloride (EC 231-589-4)
Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2)
21/01/2021
21/01/2021
08/03/2021
08/03/2021
Details
Cobalt(II) carbonate 208-169-4 513-79-1
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90-day): oral
02/09/2011
02/09/2011
02/09/2011
17/10/2011
17/10/2011
17/10/2011
Details
Barium carbonate 208-167-3 513-77-9 Long-term toxicity to fish 29/04/2011 14/06/2011 Details
Barium carbonate 208-167-3 513-77-9
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
16/12/2011
16/12/2011
30/01/2012
30/01/2012
Details
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
02/06/2014
02/06/2014
17/07/2014
17/07/2014
Details
1,1,3,3-tetramethylbutyl peroxyneodecanoate 257-077-0 51240-95-0 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant 01/09/2017 16/10/2017 Details
4-(1-oxo-2-propenyl)-morpholine 418-140-1 5117-12-4 Genetic toxicity in vivo 21/09/2020 05/11/2020 Details
(3-chloropropyl)triethoxysilane 225-805-6 5089-70-3
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
26/10/2022
26/10/2022
12/12/2022
12/12/2022
Details
N-isopropylhydroxylamine 225-791-1 5080-22-8
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
18/02/2014
18/02/2014
18/02/2014
04/04/2014
04/04/2014
04/04/2014
Details
Guanidinium nitrate 208-060-1 506-93-4
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
25/09/2012
25/09/2012
12/11/2012
12/11/2012
Details
Potassium dicyanoargentate 208-047-0 506-61-6 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
1,3-dioxepane 208-015-6 505-65-7
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (two-generation reproductive toxicity)
Sub-chronic toxicity (90 day): inhalation
15/07/2011
15/07/2011
15/07/2011
29/08/2011
29/08/2011
29/08/2011
Details
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 225-716-2 5026-74-4
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Details
p-(2,3-epoxypropoxy)-N,N-bis(2,3-epoxypropyl)aniline 225-716-2 5026-74-4
Genetic toxicity in vivo || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Reproductive toxicity (two-generation reproductive toxicity) || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
Sub-chronic toxicity (90-day): oral || Note: testing proposed with the m-isomer of the substance (CAS 71604-74-5)
15/07/2014
15/07/2014
15/07/2014
15/07/2014
29/08/2014
29/08/2014
29/08/2014
29/08/2014
Details
Hexan-6-olide 207-938-1 502-44-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/12/2020
16/12/2020
01/02/2021
01/02/2021
Details
N-(3-aminopropyl)iminodiethanol 225-642-0 4985-85-7
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
14/08/2014
14/08/2014
28/09/2014
28/09/2014
Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/11/2015
01/11/2015
16/12/2015
16/12/2015
Details
8,9,10-trinorborn-2-ene 207-866-0 498-66-8
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/06/2011
16/06/2011
01/08/2011
01/08/2011
Details
arbonohydrazide 207-837-2 497-18-7
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
18/02/2014
18/02/2014
04/04/2014
04/04/2014
Details
Quinazolin-4(1H)-one 207-735-8 491-36-1 Genetic toxicity in vivo 23/11/2020 07/01/2021 Details
Fluoren-9-one 207-630-7 486-25-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/11/2020 07/01/2021 Details
2-phenoxyethyl acrylate 256-360-6 48145-04-6
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
15/04/2014
15/04/2014
30/05/2014
30/05/2014
Details
Tetrasodium 2-(4-fluoro-6-(2-(2-sulfonatoethansulfonyl)ethylamino)-1,3,5-triazin-2-ylamino)-5-hydroxy-6-(2-(2-hydroxy-5-sulfonatophenylazo)-4,5-dimethoxyphenylazo)-7-sulfonatonaphthalene-1-sulfonatocuprate(II) 442-640-7 479541-17-8 Genetic toxicity in vivo 03/10/2023 17/11/2023 Details
1,8-naphthylenediamine 207-529-8 479-27-6 Genetic toxicity in vivo 22/04/2021 07/06/2021 Details
Octylphosphonic acid 225-218-5 4724-48-5 Sub-chronic toxicity (90-day): oral 03/04/2023 22/05/2023 Details
Octylphosphonic acid 225-218-5 4724-48-5 Reproductive toxicity (pre-natal developmental toxicity) 16/05/2014 30/06/2014 Details
Calcium carbonate 207-439-9 471-34-1 Sub-chronic toxicity (90 day): inhalation 15/07/2011 29/08/2011 Details