Previous Testing Proposals

Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
hexadecyltrimethoxysilane 240-464-3 16415-12-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/11/2021
25/11/2021
10/01/2022
10/01/2022
Saccharomyces cerevisiae cell wall, extracted 949-711-6 -
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8)
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Saccharomyces cerevisiae, lysate (EC 305-230-8)
25/11/2021
25/11/2021
10/01/2022
10/01/2022
1,2-diacetoxybut-3-ene 421-720-5 18085-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022
1,3-Benzenediamine, coupled with diazotized m-phenylenediamine, acetates 282-617-7 84281-74-3 Genetic toxicity in vivo 25/11/2021 10/01/2022
4,4'-methylenediphenyl diisocyanate 202-966-0 101-68-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/11/2021 10/01/2022
4-methylmorpholine 203-640-0 109-02-4 Sub-chronic toxicity (90-day): oral 25/11/2021 10/01/2022
C,C'-azodi(formamide) 204-650-8 123-77-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/11/2021 10/01/2022
Diundecyl phthalate 222-884-9 3648-20-2 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022
Magnesium metaborate 237-235-5 13703-82-7 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022
Reaction products of 5,5-dimethylhydantoin and ethylene oxide 701-388-0 - Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022
Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1) 701-400-4 - Genetic toxicity in vivo 25/11/2021 10/01/2022
Reaction products of amines, polyethylenepoly-, triethylenetetramine fraction and copper sulphate (1:1) 701-399-0 - "Genetic toxicity in vivo || Note: testing proposed with Reaction products of amines, polyethylenepoly-, tetraethylenepentamine fraction and copper sulphate (1:1) (EC 701-400-4)" 25/11/2021 10/01/2022
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts 939-382-7 - Genetic toxicity in vivo 25/11/2021 10/01/2022
Reaction products of tetrazotized 5-amino-2-[(E)-2-(4-amino-2-sulfophenyl)ethenyl]benzenesulfonic acid with 6-amino-4-hydroxynaphthalene-2-sulfonic acid and 4-amino-5-hydroxynaphthalene-2,7-disulfonic acid in 2-[bis(2-hydroxyethyl)amino]ethanol 916-899-6 - Long-term toxicity to fish 25/11/2021 10/01/2022
Sulphamidic acid 226-218-8 5329-14-6 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022
SUMILIZER GP 442-450-4 - Long-term toxicity to fish 25/11/2021 10/01/2022
Tetraammineplatinum dichloride 237-706-5 13933-32-9 Genetic toxicity in vivo 25/11/2021 10/01/2022
Vinylene carbonate 212-825-5 872-36-6 Reproductive toxicity (pre-natal developmental toxicity) 25/11/2021 10/01/2022
Lithium bis(fluorosulfonyl)imide 686-526-7 171611-11-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/10/2021
21/10/2021
21/10/2021
07/12/2021
07/12/2021
07/12/2021
Ditolyl ether 248-948-6 28299-41-4
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
21/10/2021
21/10/2021
07/12/2021
07/12/2021
2,7-naphthalenedisulfonic acid, 4-amino-5-hydroxy-, diazotized, coupled with diazotized 2-amino-4,6-dinitrophenol, diazotized 4-nitrobenzenamine and resorcinol, sodium salts 232-380-0 8011-86-7 Genetic toxicity in vivo 21/10/2021 07/12/2021
2-(2-(2-ethoxyethoxy)ethoxy)ethanol 203-978-9 112-50-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) 21/10/2021 07/12/2021
3,6,9,12-tetraoxotridecanol 245-883-5 23783-42-8 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2-(2-(2-methoxyethoxy)ethoxy)ethanol (EC 203-962-1) 21/10/2021 07/12/2021
Carboxylic acids, di-, C4-6 271-678-5 68603-87-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with adipic acid (EC 204-673-3) 21/10/2021 07/12/2021
Decanal 203-957-4 112-31-2 Reproductive toxicity (pre-natal developmental toxicity) 21/10/2021 07/12/2021
Disodium [2,4-dihydro-4-[(2-hydroxy-5-nitrophenyl)azo]-5-methyl-2-phenyl-3H-pyrazol-3-onato(2-)][3-hydroxy-4-[(2-hydroxy-1-naphthyl)azo]-7-nitronaphthalene-1-sulphonato(3-)]chromate(2-) 274-490-1 70236-60-1 Genetic toxicity in vivo 21/10/2021 07/12/2021
n-methyl-n-[c18-(unsaturated)alkanoyl]glycine 701-177-3 - Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2021 07/12/2021
N-Phenyl-diethanolamine, reaction products with formaldehyde 942-131-4 - Reproductive toxicity (pre-natal developmental toxicity) 21/10/2021 07/12/2021
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 - Sub-chronic toxicity (90-day): oral 21/10/2021 07/12/2021
Propanamide, 2-hydroxy-N,N-dimethyl- 609-066-0 35123-06-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 21/10/2021 07/12/2021
Fatty acids, C12-14 (even numbered), methyl ester 629-776-4 308065-15-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2021
30/09/2021
30/09/2021
15/11/2021
15/11/2021
15/11/2021
n4,n4'-hexane-1,6-diylbis[n-butyl-6-chloro-n,n'-bis(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,5-triazine-2,4-diamine] 835-183-3 83420-16-0
Bioaccumulation aquatic / sediment
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2021
30/09/2021
30/09/2021
15/11/2021
15/11/2021
15/11/2021
Tetrakis(phenylmethyl)thioperoxydi(carbothioamide) 404-310-0 10591-85-2
Long-term toxicity to fish
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2021
30/09/2021
30/09/2021
15/11/2021
15/11/2021
15/11/2021
3-(trimethoxysilyl)propyl isocyanate 239-415-9 15396-00-6
Genetic toxicity in vivo
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: it is proposed to use the information from an ongoing study with 3-(trimethoxysilyl)propylamine (EC 237-511-5)
30/09/2021
30/09/2021
15/11/2021
15/11/2021
Ethylene 200-815-3 74-85-1
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2021
30/09/2021
15/11/2021
15/11/2021
Saccharomyces cerevisiae, lysate 305-230-8 94350-12-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
30/09/2021
30/09/2021
15/11/2021
15/11/2021
1,1'-(methylenedi-p-phenylene)bismaleimide 237-163-4 13676-54-5 Reproductive toxicity (pre-natal developmental toxicity) 30/09/2021 15/11/2021
3-methoxy-3-methylbutan-1-ol 260-252-4 56539-66-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 30/09/2021 15/11/2021
A mixture of: esters of C14-C15 branched alcohols with 3,5-di-t-butyl-4-hydroxyphenyl propionic acid; C15 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate; C13 branched and linear alkyl 3,5-bis(1,1-dimethylethyl)-4-hydroxybenzenepropanoate 413-750-2 - Reproductive toxicity (pre-natal developmental toxicity) 30/09/2021 15/11/2021
benzenesulfonic acid, 4-c10-13-alkyl derivs.-, salts with amines, c16-c18 (even numbered) alkyl 953-378-2 - Long-term toxicity to fish 30/09/2021 15/11/2021
BICYCLO[3.1.1]HEPT-2-ENE,2,6,6-TRIMETHYL-,POLYMER WITH 6,6-DIMETHYL-2-METHYLENEBICYCLO[3.1.1]HEPTANE 608-613-0 - Reproductive toxicity (pre-natal developmental toxicity) 30/09/2021 15/11/2021
Dodecanoic acid, 2,2-dimethyl-3-oxopropyl ester 468-880-2 102985-93-3 Long-term toxicity to fish 30/09/2021 15/11/2021
Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (101-68-8), Octylamine (111-86-4) and Cyclohexylamine (108-91-8) 926-119-6 - Long-term toxicity to fish || Note: testing proposed with Reaction mass of 4,4'-methylenediphenyl diisocyanate and Amines, soya alkyl (EC 905-837-3) and Reaction product of 4,4'-methylenediphenyl diisocyanate (MDI) (CAS: 101-68-8), Octylamine (111-86-4) and Hexamethylenediamine (124-09-4) (EC no 924-670-7) 30/09/2021 15/11/2021
Sodium 2,4,5-trichlorobenzenesulphonate 258-548-3 53423-65-7 Genetic toxicity in vivo 30/09/2021 15/11/2021
Alkane 6 438-390-3 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (extended one-generation reproductive toxicity study || Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Dodecene, Dimer (EC 814-509-8), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9) and Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)
26/08/2021
26/08/2021
26/08/2021
11/10/2021
11/10/2021
11/10/2021
Branched hexatriacontane 417-070-7 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 1-Dodecene, dimer, hydrogenated (EC 604-768-3) and 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1), 1-decene, dimer (EC 917-709-4), 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1-Decene, tetramer, mixed with 1-decene trimer, hydrogenated (EC 614-695-9), 1-Dodecene, Dimer (EC 814-509-8 ), Dec-1-ene, homopolymer, hydrogenated Dec-1-ene, oligomers, hydrogenated (EC 500-183-1)
26/08/2021
26/08/2021
26/08/2021
11/10/2021
11/10/2021
11/10/2021
N,N-dimethyl-N'-(2,2,6,6-tetramethylpiperidin-4-yl)propane-1,3-diamine 278-817-9 78014-16-1
Sub-chronic toxicity (90-day): oral
Genetic toxicity in vivo
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
26/08/2021
11/10/2021
11/10/2021
11/10/2021
(1-methylethylidene)di-4,1-phenylenetetraphenyl diphosphate 425-220-8 5945-33-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
3-chloropropyltrimethoxysilane 219-787-9 2530-87-2
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021
6,8-Dioxabicyclo[3.2.1]octan-4-one, (1S,5R) (Cyrene) 807-130-4 53716-82-8
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
26/08/2021
26/08/2021
11/10/2021
11/10/2021



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