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Previous Testing Proposals

Previous Testing Proposals

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
1-ethoxy-2-(2-methoxyethoxy)ethane 213-690-5 1002-67-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
25/05/2020
09/07/2020
09/07/2020
09/07/2020
1,4-dimethylpiperazine 203-412-0 106-58-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
2,2-dimethyl-1,3-dioxolan-4-ylmethanol 202-888-7 100-79-8
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
2,3-epoxypropyl neodecanoate 247-979-2 26761-45-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate; 2,2-bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane triacrylate 239-701-3 15625-89-5
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Ashes (residues), nonhazardous municipal solid waste 937-417-0 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
Dipotassium bis[μ-[tartrato(4-)-O1,O2:O3,O4]]diantimonate(2-) , stereoisomer 234-293-3 11071-15-1
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
N'-(1,3-dimethylbutylidene)-3-hydroxy-2-naphthohydrazide 435-860-1 214417-91-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
25/05/2020
25/05/2020
09/07/2020
09/07/2020
(3-chloropropyl)dimethoxymethylsilane 242-056-0 18171-19-2 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
(R)-p-mentha-1,8-diene 227-813-5 5989-27-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020
1,2-Benzenedicarboxylic acid, benzyl C7-9-branched and linear alkyl esters 701-339-3 - Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020
1,3-Propanediamine, N-[3-((C11-14, C13-rich)oxy)propyl]- branched acetate 931-295-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE 921-042-4 - Genetic toxicity in vivo 25/05/2020 09/07/2020
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (EC 219-137-4) 25/05/2020 09/07/2020
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020
4,4'-isopropylidenedi-o-cresol 201-240-0 79-97-0 Genetic toxicity in vivo 25/05/2020 09/07/2020
[1,3-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 218-664-7 2212-81-9 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide CAS: 25155-25-3)” 25/05/2020 09/07/2020
Choline hydroxide 204-625-1 123-41-1 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Choline chloride (EC 200-655-4) 25/05/2020 09/07/2020
Dichlorobis(η-cyclopentadienyl)titanium 215-035-9 1271-19-8 Genetic toxicity in vivo 25/05/2020 09/07/2020
Dimethoxymethylsilane 240-914-9 16881-77-9 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
hexadecyltrimethoxysilane 240-464-3 16415-12-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/05/2020 09/07/2020
Lithium phosphorodifluoridate 643-080-8 24389-25-1 Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020
Lithium tetrafluoroborate, anhydrous 238-178-9 14283-07-9 Genetic toxicity in vivo 25/05/2020 09/07/2020
N-(2-hydroxyethyl)-N-[2-[(1-oxooctyl)amino]ethyl]-β-alanine 264-761-2 64265-45-8 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Amphoacetates C8-C18 (EC 931-291-0) || Note: Testing proposal is based on concern identified by the registrant. 25/05/2020 09/07/2020
p-tert-butylstyrene 217-126-9 1746-23-2 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. 25/05/2020 09/07/2020
Phosphoric acid, 2-ethylhexyl ester 235-741-0 12645-31-7 Reproductive toxicity (pre-natal developmental toxicity) 25/05/2020 09/07/2020
Platinum(IV) aqua hydroxo nitrato complexes 701-319-4 - Genetic toxicity in vivo 25/05/2020 09/07/2020
Platinum, 1,3-diethenyl-1,1,3,3-tetramethyldisiloxane complexes 701-315-2 - Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant. 25/05/2020 09/07/2020
Reaction mass of 4,4,13,13-tetraethoxy-3,14-dioxa-8,9-dithia-4,13-disilahexadecane and 4,4,14,14-tetraethoxy-3,15-dioxa-8,9,10-trithia-4,14-disilaheptadecane 915-748-1 - Sub-chronic toxicity (90-day): oral || Note: testing proposed with polysulfides, bis[3-(triethyoxysilyl)propyl (CAS No 211519-85-6) 25/05/2020 09/07/2020
Reaction mass of sodium 1-methoxy-1-oxohexadecane-2-sulphonate and sodium methyl 2-sulphooctadecanoate 911-616-2 - Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
Sodium 1-hydroxyethanesulphonate 213-037-4 918-04-7 Genetic toxicity in vivo 25/05/2020 09/07/2020
triethoxy(methyl)silane 217-983-9 2031-67-6 Sub-chronic toxicity (90-day): oral 25/05/2020 09/07/2020
Zinc bis(benzenesulphinate) 246-148-1 24308-84-7 Genetic toxicity in vivo 25/05/2020 09/07/2020
Distillates (petroleum), hydrodesulfurized middle 265-183-3 64742-80-9 Genetic toxicity in vivo 14/05/2020 29/06/2020
Distillates (petroleum), hydrotreated middle 265-148-2 64742-46-7 Genetic toxicity in vivo 14/05/2020 29/06/2020
Gas oils (petroleum), hydrodesulfurized 265-182-8 64742-79-6 Genetic toxicity in vivo 14/05/2020 29/06/2020
Benzyldimethylamine 203-149-1 103-83-3
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
23/03/2020
07/05/2020
07/05/2020
07/05/2020
(octahydro-4,7-methano-1H-indenediyl)bis(methylene) diacrylate 255-901-3 42594-17-2
Reproductive toxicity (pre-natal developmental toxicity)
Bioaccumulation test (Bioconcentration: Flow-through Fish Test)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
4-(1,1-dimethylethyl)cyclohexyl acrylate 282-104-8 84100-23-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
N,N''-(4-methyl-m-phenylene)bis[N',N'-dimethylurea] 241-523-6 17526-94-2
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
Reaction products of 1H-Imidazole-1-ethanol, 4,5-dihydro-, 2-(C7-C17 odd-numbered, C17-unsatd. alkyl) derivs. and sodium hydroxide and chloroacetic acid 931-291-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
23/03/2020
23/03/2020
07/05/2020
07/05/2020
(Z)-4-[C11-13 (branched) alkylamino]-4-oxo-2-butenoic acid 701-116-0 - Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) 23/03/2020 07/05/2020
2-(1-oxa-4-azaspiro[4.5]dec-4-yl)ethyl methacrylate 224-116-8 4203-89-8 Genetic toxicity in vivo 23/03/2020 07/05/2020
2-[[(butylamino)carbonyl]oxy]ethyl acrylate 264-036-0 63225-53-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 23/03/2020 07/05/2020
2-isocyanatoethyl methacrylate 250-284-7 30674-80-7 Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020
4-phenylbutenone 204-555-1 122-57-6 Genetic toxicity in vivo 23/03/2020 07/05/2020
Dialkyl-methyl-dihydro-heteropolycyle 815-131-6 913171-06-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 23/03/2020 07/05/2020
Dimethyl (p-methoxybenzylidene)malonate 231-185-8 7443-25-6 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 23/03/2020 07/05/2020
Dioctyltin dilaurate 222-883-3 3648-18-8 Reproductive toxicity (pre-natal developmental toxicity) 23/03/2020 07/05/2020



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