Precedenti/Esito
Precedenti/Esito
Precedenti/Esito
This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.
To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.
Cobalt hydroxide oxide | 234-614-7 | 12016-80-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt lithium dioxide | 235-362-0 | 12190-79-3 |
Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. Sub-chronic toxicity (90 day): inhalation
|| Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt oxalate | 212-409-3 | 814-89-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt oxalate | 212-409-3 | 814-89-1 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt oxide | 215-154-6 | 1307-96-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt oxide | 215-154-6 | 1307-96-6 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2) |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
cobalt sulphate | 233-334-2 | 10124-43-3 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4) Genetic toxicity in vivo |
21/01/2021 21/01/2021 |
08/03/2021 08/03/2021 |
Details | |
Cobalt sulphide | 215-273-3 | 1317-42-6 |
Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. Reproductive toxicity (extended one-generation reproductive toxicity study) Sub-chronic toxicity (90 day): inhalation
|| Note: testing proposed with Tricobalt tetraoxide (EC 215-157-2)
|| Note: Testing proposal is based on concern identified by the registrant |
21/09/2020 21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 05/11/2020 |
Details | |
Cobalt sulphide | 215-273-3 | 1317-42-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(2+) propionate | 216-333-1 | 1560-69-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(II) 4-oxopent-2-en-2-olate | 237-855-6 | 14024-48-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(II) 4-oxopent-2-en-2-olate | 237-855-6 | 14024-48-7 |
"Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant.
" Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Cobalt(II) carbonate | 208-169-4 | 513-79-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt(II) diacetate | 200-755-8 | 71-48-7 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt, borate 2-ethylhexanoate complexes | 295-032-7 | 91782-60-4 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant |
07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 |
Details | |
Cobalt, borate neodecanoate complexes | 270-601-2 | 68457-13-6 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
02/09/2011 02/09/2011 02/09/2011 |
17/10/2011 17/10/2011 17/10/2011 |
Details | |
Cobalt, borate neodecanoate complexes | 270-601-2 | 68457-13-6 | Genetic toxicity in vivo || Note: testing proposed with Cobalt sulphate (EC 233-334-2) | 21/01/2021 | 08/03/2021 | Details | |
Cobalt, borate propionate complexes | 295-033-2 | 91782-61-5 |
Carcinogenicity
|| Note: testing proposed with Cobalt dichloride (EC 231-589-4)
|| Note: Testing proposal is based on concern identified by the registrant. Genetic toxicity in vivo
|| Note: testing proposed with Cobalt sulphate (EC 233-334-2)
|| Note: Testing proposal is based on concern identified by the registrant. |
21/09/2020 21/09/2020 |
05/11/2020 05/11/2020 |
Details | |
Coconut oil, reaction products with polyethylene glycol and trimethylolpropane | 640-964-5 | - |
Genetic toxicity in vivo Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
15/09/2011 15/09/2011 15/09/2011 |
31/10/2011 31/10/2011 31/10/2011 |
Details | |
Condensates (petroleum), vacuum tower | 265-049-4 | 64741-49-7 | Reproductive toxicity (two-generation reproductive toxicity) | 15/09/2011 | 31/10/2011 | Details | |
Condensates (petroleum), vacuum tower | 265-049-4 | 64741-49-7 |
Genetic toxicity in vivo
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuels, diesel (EC 269-822-7)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2) Reproductive toxicity (extended one-generation reproductive toxicity study)
|| Note: testing proposed with Gas oils (petroleum), light vacuum (EC 265-059-9) Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2)
- Fuels, diesel (EC 269-822-7) Sub-chronic toxicity (90 day): dermal
|| Note: testing proposed with
- Gas oils (petroleum), light vacuum (EC 265-059-9)
- Fuel oil, no. 4 (EC 270-673-5)
- Distillates (petroleum), light hydrocracked (EC 265-078-2) |
07/07/2020 07/07/2020 07/07/2020 07/07/2020 |
21/08/2020 21/08/2020 21/08/2020 21/08/2020 |
Details | |
Condensation product of N-C12-C18- alkylpropane-1,3-diamine, N-(3- aminopropyl)-N'-C12-C18- alkylpropane-1,3-diamine and formic acid | 641-088-6 | - |
Bioaccumulation aquatic / sediment Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
16/08/2011 16/08/2011 16/08/2011 |
30/09/2011 30/09/2011 30/09/2011 |
Details | |
Condensation products of dimerised fatty acids, C18-unsaturated, with N,N-dimethyl-1,3-propanediamine and 1,3-propanediamine | 605-296-0 | 162627-17-0 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90 day): oral |
14/08/2014 14/08/2014 14/08/2014 |
28/09/2014 28/09/2014 28/09/2014 |
Details | |
Condensation products of phenol and salicylaldehyde | 947-320-5 | - | Genetic toxicity in vivo | 20/05/2021 | 05/07/2021 | Details | |
Condensation products of triethanolamine with addition products of fatty acids, C18 (unsaturated) alkyl with maleic anhydride | - | - |
Long-term toxicity to fish Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
10/03/2017 10/03/2017 10/03/2017 |
25/04/2017 25/04/2017 25/04/2017 |
Details | |
Copolymer of acetonoxime and 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl isocyanate | 600-028-9 | 1001254-87-0 |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): dermal |
02/06/2014 02/06/2014 |
17/07/2014 17/07/2014 |
Details | |
Copolymer of benzenamine and formaldehyde, hydrogenated | 603-894-6 | 135108-88-2 | Reproductive toxicity (pre-natal developmental toxicity) | 14/08/2014 | 28/09/2014 | Details | |
Copper (2+), bis [N-{amino (imino-KN) methyl} urea-KO]-, nitrate (1:2) | 800-038-5 | 1071838-81-7 | Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. | 23/01/2015 | 09/03/2015 | Details | |
Copper hydroxide nitrate | 439-590-3 | 12158-75-7 | Reproductive toxicity (pre-natal developmental toxicity) | 03/11/2011 | 19/12/2011 | Details | |
Copper(I, II) sulfite | 884-197-6 | 15293-86-4 | 7.6.2 Genetic toxicity in vivo||Note: testing proposed with copper(I,II) sulfite dihydrate (CAS No. 13814-81-8) | 08/03/2024 | 22/04/2024 | Details | |
Coupling reaction products of diazotized 2-amino-6-[(2-substituted ethyl)sulfonyl]naphthalene-1-subsituted acid with 4-({4-chloro-6-[ethyl(3-{[2-(substituted oxy)ethyl]sulfonyl}phenyl)amino]-heteromonocycl-2-yl}amino)-5-hydroxynaphthalene-2,7-disubstituted acid and their sodium and potassium salts | - | - | 7.6.2 Mammalian erythrocyte micronucleus test according to OECD 474 | 03/12/2010 | 17/01/2011 | Details | |
Cyclohex-1,2-ylenediamine | 211-776-7 | 694-83-7 | Genetic toxicity in vivo | 22/09/2022 | 07/11/2022 | Details | |
Cyclohexane-1,4-dicarboxylic acid | 214-068-6 | 1076-97-7 | Reproductive toxicity (pre-natal developmental toxicity) | 27/11/2013 | 10/01/2014 | Details | |
Cyclohexane-1,4-diyldimethanol | 203-268-9 | 105-08-8 | OECD Guideline 414 (Prenatal Developmental Toxicity Study) | 19/11/2010 | 03/01/2011 | Details | |
Cyclohexanone, peroxide | 235-527-7 | 12262-58-7 | Genetic toxicity in vivo | 19/10/2020 | 03/12/2020 | Details | |
Cyclohexyldimethoxymethylsilane | 402-140-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
16/01/2012 16/01/2012 16/01/2012 |
01/03/2012 01/03/2012 01/03/2012 |
Details | |
Cyclohexyldimethylamine | 202-715-5 | 98-94-2 | Reproductive toxicity (pre-natal developmental toxicity) | 01/07/2021 | 16/08/2021 | Details | |
Cyclohexylidenebis[tert-butyl] peroxide | 221-111-2 | 3006-86-8 | Sub-chronic toxicity (90-day): oral | 21/03/2014 | 05/05/2014 | Details | |
D-glucopyranose, oligomeric, C10-16 glycosides (even numbered), carboxymethyl ethers, sodium salts | 609-542-8 | 383178-66-3 | Reproductive toxicity (pre-natal developmental toxicity) | 30/11/2015 | 14/01/2016 | Details | |
D-glucopyranose, oligomers, xylityl glycosides and 1,4 anhydro D-xylitol and D-xylitol | 446-990-1 | - |
Reproductive toxicity (pre-natal developmental toxicity) Sub-chronic toxicity (90-day): oral |
23/01/2015 23/01/2015 |
09/03/2015 09/03/2015 |
Details | |
d-Glucose, ether with glycerol | 309-496-6 | 100402-60-6 | Reproductive toxicity (pre-natal developmental toxicity) | 15/07/2014 | 29/08/2014 | Details | |
Dec-1-ene | 212-819-2 | 872-05-9 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |
decahydronaphthalene | 202-046-9 | 91-17-8 | Reproductive toxicity (two-generation reproductive toxicity) | 15/07/2011 | 29/08/2011 | Details | |
Decahydronaphthalene | 202-046-9 | 91-17-8 | Reproductive toxicity (extended one-generation reproductive toxicity study) | 23/04/2018 | 07/06/2018 | Details | |
Decamethylcyclopentasiloxane | 208-764-9 | 541-02-6 | Reproductive toxicity (pre-natal developmental toxicity) | 25/10/2017 | 11/12/2017 | Details | |
Decamethylenediamine | 211-471-9 | 646-25-3 | Reproductive toxicity (pre-natal developmental toxicity) | 03/03/2014 | 17/04/2014 | Details | |
decamethyltetrasiloxane | 205-491-7 | 141-62-8 | Reproductive toxicity (pre-natal developmental toxicity) | 16/10/2014 | 01/12/2014 | Details | |
Decanal | 203-957-4 | 112-31-2 | Reproductive toxicity (pre-natal developmental toxicity) | 21/10/2021 | 07/12/2021 | Details | |
Decane | 204-686-4 | 124-18-5 | Reproductive toxicity (two-generation reproductive toxicity) | 25/06/2012 | 09/08/2012 | Details | |
Decene | 246-870-7 | 25339-53-1 |
Reproductive toxicity (pre-natal developmental toxicity) Reproductive toxicity (two-generation reproductive toxicity) Sub-chronic toxicity (90-day): oral |
31/05/2011 31/05/2011 25/06/2012 |
15/07/2011 15/07/2011 09/08/2012 |
Details | |