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EC number: 603-837-5
CAS number: 134605-64-4
The study was performed to assess the irritancy potential
of the test material to the skin of the New Zealand White rabbit. The
study was performed to GLP and followed the EPA guideline 81-5. The test
substance was evaluated in 6 female New Zealand white rabbits. A dose of
0.5 g test substance, moistened with 0.5 mL distilled water, was applied
to the intact shorn dorsal skin site under a semi-occlusive dressing for
4 hours. The patch was then removed and the application site was washed
to remove residual test material. Skin observations were made 30
minutes, 24, 48 and 72 hours after patch removal.
A single 4-hour, semi-occluded application of the test
material to the intact skin produced no irritation effects. The test
material produced a primary irritation index (PII) of 0 and is
considered to be non-irritating to skin.
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