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Diss Factsheets
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EC number: 603-837-5 | CAS number: 134605-64-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
Weight of evidence:
Half-life, 4.5 to 6.4 days under aerobic conditions, Commission Directive 95/36/EC Annex II, Reischmann 1999.
Half-life, 4.9 days aerobic conditions, 3.1 days anaerobic conditions, Canadian pesticide guideline C:2, Reischmann 1999
Half-life, 1.5 – 2.4 days aerobic, 1.5 days anaerobic, Commission Directive 95/36/EC Annex II & Canadian pesticide guideline C:2, Reischmann 1999.
Half-life, 3.7 – 5.2 days aerobic, 4.0 to 13.0 days anaerobic, Commission Directive 95/36/EC Annex II & Canadian pesticide guideline C:2, Schulaze-Aurich 1999.
Key value for chemical safety assessment
Additional information
A weight of evidence has been provided to address biodegradation of the test material in water and sediment.
The consensus of the four studies was that the test material is rapidly degraded in various aquatic systems at 20 °C under both aerobic and anaerobic conditions. The test material was determined to have a half-life in the entire system of between 3.1 and 7.7 days; between 2.1 to 4.0 days in the aqueous phase and 1.5 to 2.4 days in sediment. At lower temperatures the half-life increased. Sterile aerobic incubations yielded much higher half-lives, 53.3 to 65 days for the entire system, where degradation occurred via hydrolysis. Metabolic patterns were comparable regardless of the type of aquatic system or the dose rate. Several metabolites were identified in four of the studies, with half-lives ranging from 2.2 days up to 458.1 days. End products were identified as carbon dioxide and bound residue.
All four studies was performed to a high standard, in line with GLP and in accordance with standardised guidelines and has thus been assigned a reliability score of 1 in line with the principles for assessing data quality set out in Klimisch (1997).
The available data are considered to be complete and the conclusion that the test material is rapidly degradable in aquatic systems at 20 °C has been taken forward for risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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