Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 603-837-5
CAS number: 134605-64-4
The study was performed to assess the acute dermal
toxicity of the test material in the Crl :CO®(SD)BR strain rat. The
study was performed to GLP and the method was designed to meet the
requirements of the EPA Guideline 81 -2.10 test animals (5 males and 5
females) were given a single, 24 -hour, semi-occluded dermal application
of the test material (slightly moistened using distilled water) to
intact skin at a dose of 2000 mg/kg body weight. Bodyweight development
were monitored during the study. All animals were subjected to gross
No signs of dermal irritation were noted. Animals showed
expected gains in bodyweight over the study period. No abnormalities
were noted at necropsy. Clinical signs were observed in 2 control males,
2 control females and 2 test females; these included: red-stained face,
wet and/or yellow-stained urogenital area, and soft stool. These four
animals returned to a normal appearance by Day 3 after treatment. The
acute dermal median lethal dose (LD50) of the test material in male and
female Crl :CO®(SD)BR rats was found to be greater than 2000 mg/kg
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again