Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 603-837-5
CAS number: 134605-64-4
LC50 >1250 mg a.i./kg d.w., NOEC 1250 mg a.i./kg d.w., Eisena fetida, 14 days, OECD 207, Palmers & Beavers 1996a.
The toxicity to soil macroorganisms was determined in an acute toxicity
study using the earthworm (Eisena fetida). The study was
performed according to GLP and in line with the standardised guideline
OECD 207. Worms were exposed to the test material for 14 days at the
following nominal concentrations: 162, 270, 450, 750 and 1250 mg a.i./kg
dry soil. Artificial soil was used as the substrate. A solvent control
was run concurrently for comparison.
Under the conditions of the test, no mortalities were observed in any of
the exposure groups. All worms appeared normal in appearance and
behaviour throughout the study. Average group body weight measurements
showed no apparent treatment-related effects and there were no
statistically significant differences (p>0.05) observed in body weight
change among worms in the treatment groups when compared to the
controls. On Day 0, all worms were either beneath the soil surface or in
the process of burrowing by the ¾ hour observation interval. On Day 7
all worms had burrowed by 3½ hours following replacement on the soil
surface following observations for mortality. No mortalities were
observed in the controls over the 14 day test period and all control
worms appeared normal in appearance and behaviour throughout the test.
The 14 day LC50 was determined to be >1250 mg a.i./kg dry soil, the
highest concentration tested. The NOEC was determined to be 1250 mg
a.i./kg dry soil.
The study was performed to a high standard, in line with GLP and
standardised guidelines. Accordingly, the study has been assigned a
reliability score of 1 in line with the principles for assessing data
quality set out in Klimisch (1997). The available data are deemed to be
relevant, reliable and adequate for the purposes of risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again